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BIOCHEMISTRY > BETAOXIDATION > Flashcards

BETAOXIDATION Flashcards

1
Q

The first three steps in beta oxidation is analogous to what other pathway?

A

CAC

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1
Q

In the Thiolase cleavage step, the two products are

A

Acetyl CoA and fatty acyl coA

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2
Q

ATPS in one molecule of Acetyl CoA

A

12

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2
Q

a-oxidation occurs in what site?

A

peroxisomes

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3
Q

How many Acetyl CoAs are consumed in the B-Oxidation of MSFA?

A

3 molecules of Acetyl CoA

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4
Q

Enzyme involved in the rate limiting step

A

Carnitine Acyl Transferase II

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6
Q

Inhibits Carnitine acyltransferase I

A

Malonyl CoA

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6
Q

What carbon number does a-oxidation act on?

A

C2/a-carbon

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7
Q

ATPs in one molecule of NADH

A

3

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8
Q

ATPS in one molecule of FADH2

A

2

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9
Q

What is propionyl CoA carboxylated into in odd beta oxidation?

A

methylmalonyl CoA

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10
Q

Main Reaction steps in Beta Oxidation

A

Oxidation, Hydration, Second Oxidation and Thiolytic Cleavage

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11
Q

In the formation of Methylmalonyl CoA, what enzyme is used?

A

Propionyl CoA carboxylase

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12
Q

where does w-oxidation occur?

A

endoplasmic reticulum

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13
Q

Final product of odd carbon beta oxidation

A

propionyl CoA

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15
Q

The number of chains there should be for it to utilize the mitochondrial transport

A

C12-C18

16
Q

Shuttle system that transports fatty acids to the mitochondrial matrix

A

Carnitine Shuttle System

17
Q

The pathway the acetyl coa from the cleavage step takes

A

Krebs Cycle

18
Q

how many carbons are removed at a time in a-oxidation?

A

1 carbon atom

19
Q

What step is skipped in the B-oxidation of MSFAs?

A

Acyl-CoA dehydrogenase step

21
Q

Rate limiting step in B-oxidation

A

Formation of Fatty Acyl CoA from acyl cartnitine as it is transported across the mitochondrial membrane to the mitochondrial matrix

22
Q

products of odd carbon beta oxidation when the 5 carbon acyl coa is cleaved

A

1 molecule of C3 propionyl CoA and 1 molecule of c2 acetyl CoA

23
Q

Methylmalonyl CoA is turned into Succinyl CoA through through what factors

A

racemace, isomerase, vitamin b12

24
Q

Glucagon’s effect on Beta oxidation

A

increases rate of Beta-Oxidation

25
Q

Enzyme present in the cytosol as Fatty acid is turned into Fatty Acyl CoA

A

Fatty Acyl coA synthase/ thiokinase

26
Q

Insulin’s effect on Beta-oxidation

A

decreases rate of Beta-Oxidation

27
Q

What carbon number does b-oxidation act on?

A

C3

28
Q

Site of Beta oxidation

A

Mitochondrial Matrix

BIOCHEMISTRY (6 decks)

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