Lipid oxidation Flashcards
Oleic acid cis double bond between
C9 and C10
First step of oxidation of oleic acid
Oleate converted to oleoyl coA
Oleoyl co A yields
3 molecules of acetyl coA and coenzyme A ester of 3 dodecenoyl coA
cis 3 enoyl coA to trans
3,2 enoyl. coA isomerase
trans 2 enoyl coA to L beta hydroxyl acyl coA
enoyl coA hydratase
Omega oxidation enzym3es located in
ER of liver and kidney
Omega oxidation enzymes
Mixed function oxidases
Alcohol dehydrogenased
Aldehyde dehydrogenase
Gets fatty acid with carbon group at each end
Omega oxidation end products
Succinic acid
Adipic acid
Alpha oxidation happens in
Peroxisomes of animal cells by alpha oxidation
Alpha oxidation happens in
Peroxisomes of animal cells
Major dietary methylated fatty acid is
Phytanic acid
Alpha oxidation yields
Co2 and fatty acid with one atom. Less