Lipid metabolism Flashcards
Lipase converts
Triacyl glycerol to di acyl monoacyl glycerol
After going to intestinal surface changes to
Triacylglycerol and cholesterol called chylomicrons
Apolipoprotein responsible for
Transport of triacylglycerol, phospholipids, cholesterol
Apolipoprotein structure
Hydrophobic lipids at the core
Hydrophilic
protein sidechains and lipid heads at surface
Adipose tissue chylomicrons gets converted into
Changes to triacyl glycerol
Lipase access is prevented by
Perilipins
Major perilipin surrounding lipid molecules
PerilipinA
Adenylate cyclase produces?
cAMP and phospholylates protein kinase A
Perilipin hyperphosphorylated bg
Protein kinase A
Fatty acid oxidation in animal cells happen
In mitochondria
Transport mechanism. Of fatty acids
Carnitine shuttle
Oxidation of fatty acids stages
Activation in cytoplasm
Transport to mitochondria
Oxidation to acetyl coA
Carnitine shuttle first enzyme
Acyl coA synthetase
Two enzymes in carnitine cycle
CAT 1 CAT 2
Hydroxyl group of carniti e
Beta hydroxy gamma trimethyl ammonium butyrate