Lipid Lowering effects

Question 1

Statins

Answer 1

40% LDL reduction
10-20% TG reduction
10% HDL increase

Question 2

Fibrates

Answer 2

10% LDL modest reduction
40% TG reduction (by reduce circulating VLDL)
10-20% HDL elevation

Question 3

Ezetimibe

Answer 3

Alone
19% LDL
2% TG
0.5% HDL increase

+Statin
34-41% LDL
20-25% TG
7-8% HDL increase

Question 4

Niacin

Answer 4

10-20% LDL reduction
20-40% TG reduction
10-30% HDL elevation