lipid disorders without fredricksons classification

Question 1

Lipid disorders

Answer 1

dyslipidemia

Question 2

Elevated lipoproteins in the blood particularly LDL and VLDL

Answer 2

Hyperlipoproteinemia

Question 3

Low level of lipoproteins

Answer 3

Hypolipoproteinemia

Question 4

3 types of Hyperlipproteinemia

Answer 4

Hypercholesterolemia
Hypertriglyceridemia
Combined hyperlipidemia

Question 5

2 types of hyoplipoproteinemia

Answer 5

Hypoalphalipoproteinemia
Hypobetalipoproteinemia

Question 6

Deposition of fats in the skin resulting to yellow patch or nodules

Answer 6

Palmar Xanthomas

Question 7

Rare inherited disorder with severe low or total absence of HDL.

Answer 7

Tangier’s disease

Question 8

Mutation in ABCA 1 gene which responsible for HDL production.
High risk of developing atherosclerosis and cardiovascular disease.

Answer 8

Tangier’s disease

Question 9

Bassen-Kornzweig syndrome

Answer 9

Abetalipoproteinemia

Question 10

Autosomal recessive, No VLDL,LDL or chylomicrons in the blood.

Answer 10

Abetalipoproteinemia

Question 11

Deficiency of Apo B48 and B100 the result to impaired fat absorption in the intestine and inability of the liver to synthesize fats.

Answer 11

Abetalipoproteinemia

Question 12

Mutation in microsomal triglycerides transfer protein (MTTP) gene responsible for production apo B-containing lipoproteins resulting to low or no VLDL, LDL or chylomicrons.

Answer 12

Abetalipoproteinemia

Question 13

Patient may develops retinitis pigmentosa, acanthocytosis, spinocerebellar degeneration, low fat- soluble vitamins and steatorrhea.

Answer 13

Abetalipoproteinemia

Question 14

Lipid storage diseases Also known as

Answer 14

lipidoses

Question 15

Group of inherited metabolic disorders in which lipids are accumulated in cells and tissues.
Deficiency in enzyme responsible for metabolism of lipids.
Prolong accumulation of lipids causes permanent damage different tissues and organs.

Answer 15

lipidoses