difference between hypoalphalipoproteinemia and hypobetalipoproteinemia Flashcards

1
Q
  1. Which lipoprotein is primarily deficient in hypoalphalipoproteinemia?
    a) Chylomicrons b) VLDL c) IDL d) HDL e) LDL
A

D

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2
Q
  1. Which lipoprotein is primarily deficient in hypobetalipoproteinemia? a) Chylomicrons b) VLDL c) IDL d) HDL e) LDL
A

E

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3
Q
  1. Which of the following is a genetic defect commonly associated with hypoalphalipoproteinemia? a) ABCA1 transporter gene mutation b) ApoE deficiency c) LDL receptor deficiency d) LPL deficiency
A

A

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4
Q

Which statement is TRUE regarding the cardiovascular risk associated with hypoalphalipoproteinemia? a) It does not increase the risk of cardiovascular disease. b) It is associated with a somewhat increased risk of premature CHD, but not as strong as disorders that increase LDL-C. c) It dramatically increases the risk of cardiovascular disease, similar to disorders that increase LDL-C. d) It is associated with a higher risk of stroke.

A

B

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5
Q

Which of the following is TRUE regarding hypobetalipoproteinemia? a) It is associated with a significant increase in cardiovascular disease risk. b) It is always caused by a defect in the ApoB gene. c) It can also present with low levels of ApoB. d) It is associated with increased levels of LDL-C.

A

C

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6
Q

Which of the following conditions is an extreme form of hypoalphalipoproteinemia? a) Familial hypercholesterolemia b) Dysbetalipoprotenemia c) Tangier disease d) Hypertriglyceridemia

A

C

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7
Q

What is the typical HDL-C concentration range in individuals with Tangier disease? a) 20-30 mg/dL b) 10-20 mg/dL c) 5-10 mg/dL d) 1-2 mg/dL

A

D

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8
Q

READ

A

Hypoalphalipoproteinemia is characterized by low levels of HDL cholesterol, also known as the “good” cholesterol. HDL helps remove excess cholesterol from the bloodstream. Low levels of HDL cholesterol can increase the risk of heart disease.

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9
Q

READ

A

Hypobetalipoproteinemia is characterized by low levels of LDL cholesterol, also known as the “bad” cholesterol. LDL cholesterol contributes to plaque buildup in the arteries, which can lead to heart disease. Low levels of LDL cholesterol are generally considered beneficial for cardiovascular health.

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10
Q

Characterized by low levels of HDL cholesterol.

A

hypoalphalipoproteinemia

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11
Q

Characterized by low levels of LDL cholesterol.

A

hypobetalipoproteinemia

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12
Q

Associated with an increased risk of cardiovascular disease.

A

hypoalphalipoproteinemia

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13
Q

Associated with a decreased risk of cardiovascular disease.

A

hypobetalipoproteinemia

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14
Q

Often caused by mutations in the ABCA1 gene.

A

hypoalphalipoproteinemia

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15
Q

Often caused by mutations in the APOB gene.

A

hypobetalipoproteinemia

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16
Q

Tangier disease is an extreme form of this condition.

A

hypoalphalipoproteinemia