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Clinical medicine A > Lipid Disorders > Flashcards

Lipid Disorders Flashcards

1
Q

blocks cholesterol from being absorbed

A

ezetimibe

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2
Q

myalgias, diarrhea, fatigue

excreted in feces

A

ezetimibe

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3
Q

increases LDL clearance by inhibiting binding to LDL receptors

A

PCSK9 inhibitors

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4
Q

URI symptoms
gastroenteritis
dizziness
myalgias

A

SE of PCSK9 inhibitors

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5
Q

no known limitation in renal or liver failure, given SC

A

PCSK 9 inhibitors

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6
Q

PCSK9 inhibitors meds

A

alirocumab
avolocumab

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7
Q

Adenosine Triphosphate-citrate Lyase inhibitor, inhibits cholesterol synthesis in liver

A

Bempedoic acid

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8
Q

needed for additional LDL reduction after max toleration of statin therapy

A

bempedoic acid

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9
Q

bempedoic acid/ezetimibe combo med name

A

nexlizet

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10
Q

SE of gout/hyperuricemia

A

bempedoic acid

also seen:
tendon rupture
muscle spasms
abdominal pain
cold/flu symptoms

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11
Q

tendon rupture
muscle spasms
abdominal pain
cold/flu symptoms

A

bempedoic acid

also seen:
gout hyperuricemia

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12
Q

interfering RNA agent of production of PCSK9

A

inclisiran

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13
Q

what are the bile acid sequestrants

A

cholestyramine
colestipol
colesevelam

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14
Q

binds to bile acids in the intestines requiring liver to excrete more bile

A

bile sequestering agents

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15
Q

SE
nausea, bloating, cramping, hepatotoxicity, increased TGs

A

bile acid sequestrians

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Clinical medicine A (32 decks)

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