Lipid digestion

Question 1

presence of lipid in acid chyme (small intestine) results in what

Answer 1

release of CCK and GIP (cholecystekitin and gastric inhibitory peptide); release of bile salts and gastric juice. CCK causes the realease of bile.

Question 2

how do bile salts effect lipids?

Answer 2

Bile salts are amphipathic, causing emulsification of lipids, increasing their surface area. lipid droplets become emulsion droplets

Question 3

Luminal digestion of lipids

Answer 3

lipilytic enzymes in pancreatic juice, Lipase and coenzyme colipase.phospholipase turns phospholipids into lysophospholipids + fatty acid. cholesterol esterase, cholesterol ester -> cholesterol + FA

Question 4

Lipid absorption

Answer 4

lipolytic products combine with bile salts and phopspholipids. this becomes a water soluble micelle, which diffuse into the glycocalyx. Lipolytic products diffise.

Question 5

fate of bile salts collected in the glycocalyx

Answer 5

released back into thelumen ,. via the ileum; recycled back to the liver. enterohepatic cycle

Question 6

what happens to the lipolytic products after absorption

Answer 6

resynthesised to triglycerides, phospholipids and cholesterol esters in the endoplasdmic reticululum

Question 7

what is a chylomicron?

Answer 7

apolipoprotein added to a lipid vesicle creates a chylomicron. apolipoproteins can stabilise the surface of the vesicle and direct its metabolism.

Question 8

after chylomicron is created..

Answer 8

released by exocytosis; they diffuse into viluss lacteal -> thoracic duct-> into blood circulation.