Lipid Composition and Structural Organization Flashcards

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1
Q

Interactions holding together lipid bilayer:

A

Van der Waal & hydrophobic

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2
Q

3 Classes of Lipids

A

Phosphoglycerides, Sphingolipids, & Cholesterol (Sterol)

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3
Q

Phosphoglyceride

A

hydrophobic tail, glycerol-3-phosphate, & polar head group

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4
Q

Sphingolipid

A

made up of sphingosine, fatty acyl chain, amino alcohol, & polar head group

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5
Q

Cholesterol/Sterol

A

ring structure with hydroxyl head group

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6
Q

Factors affecting bilayer fluidity:

A

lipid composition, structure of tails (shorter tails/double bonds=increased fluidity), temperature, cholesterol content (inhibits fluidity)

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7
Q

Site of phosphoglyceride synthesis

A

cytosolic side of endoplasmic reticulum

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8
Q

Site of Sphingolipid synthesis

A

exoplasmic face (luminal side) of Golgi complex

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9
Q

Lipids abundant in membrane outer leaflet

A

sphingomyelin & phosphatidylcholine

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10
Q

Lipids abundant in membrane inner leaflet

A

phosphatidylethanolamine, phosphatidylserine, & phosphatidylinositol

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11
Q

Lipids evenly distributed between membrane leaflets

A

cholesterol

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12
Q

Flippase

A

enzyme that can move certain phospholipids from one leaflet to the other; ATP dependent

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