Lipid catabolism

Question 1

Where does fatty acid oxidation happen?

Answer 1

Matrix

Question 2

Product of beta oxidation?

Answer 2

Acetyl co A which can enter citric acid cycle

Question 3

Steps before oxidation

Answer 3

1. Activation by binding of CoA
2. Transport by carnitine shuttle ( acyl carnitine)
   When inside carnitine is recycled
3. acyl coA is oxidised in 4 steps to make acetyl coA and 1FADH and 1NADH

Question 4

Steps of beta oxidation

Answer 4

1. acylcoA is oxidised to unsaturated alpha and beta species (1fadh2)
2. You add water To double bond making an alcohol
3. Alcohol is oxidised to a ketone making NADH
4. You add a coA-S-H to ketone making an acetyl coA