Kreb's cycle Flashcards
Mnemonic 1
Can I Keep Selling Substances For Money, Officer?
Mnemonic 2
So At Disco Devil Sipped Down Five Drinks
Where is CO2 produced?
Where loss of carbon atoms happens , so from
Isocitrate»_space; a-ketoglutarate
a-keto»_space; succynil co a
Where is NADH produced?
Where CO2 is lost and in the final step so,
Isocitrate»_space; a-ketoglutarate
A-keto»_space; succynil co a
malate»_space; oxaloacetate
Where is FADH2 produced?
from Succinate»_space; Fumarate
Where is GTP (ATP) produced?
From Succynil coA»_space; Succinate
Steps of Krebs cycle
- Claisen condensation
4+2 = 6 - Isomerization
- Oxidative decarboxylation yields NADH
- Oxidative decarboxylation yields NADH
- Substrate-level phopshorylation yields GTP
- Dehydrogenation yields FADH2
- Hydration
- Dehydrogenation yields NADH
What type of enzymes ?
All dehydrogenase except for the first and fifth which are syntheses and the second and penultimate which are aconitase and fumarate
What are the products of prep phase per one pyruvate?
NADH
CO2
What are the products of prep phase per 1 glucose (so 2 pyruvate)?
2 NADH
2CO2
What are the products of TCA per one pyruvate?
2 CO2
3 NADH
1 ATP
1FADH2
What are the products of TCA per 1 glucose (so 2 pyruvate)?
4 CO2
6 NADH
2 ATP
2 FADH2
What are products of prep. phase + TCA ?
8 NADH
6 CO2
2 ATP
2 FADH2
How many enzymes make the Pyruvate Dehydrogenase Complex?
3
How many coenzymes does PDH require?
5
