Linear Polyketides And Polyethers Flashcards

0
Q

Source of mupirocin

A

Pseudomonas fluorescens

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1
Q

Source of discodermolide

A

Discodermia dissoluta

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2
Q

Source of lasalocid A

A

Streptomyces lasaliensis

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3
Q

Source of monensin A

A

Streptomyces cinnamonensis

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4
Q

Source of okadaic acid

A

Dinophysis sp.

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5
Q

Source of brevetoxin A and B

A

Karenia brevis

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6
Q

Sources of ciguatoxin

A

Gymnothorax javanicus and Lutjanus bohar

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7
Q

Source of halichondrins

A

Halichondria okadai

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8
Q

Sources of Zaragosic acid A

A

Sporomiella intermedia and Leptodontium elatius

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9
Q

Most potent natural promoter of tubulin assembly

A

Discodermolide

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10
Q

Mixture of pseudomonic acids

A

Mupirocin

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11
Q

Esters of monic acids with C9 saturated fatty acid

A

Pseudomonic acids

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12
Q

Potent inhibitor of protein phosphatases

A

Okadaic acid

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13
Q

Red tide blooms of dinoflagellates, causative agents of neurotoxic shellfish poisoning

A

Brevetoxin A and B

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14
Q

Dinoflagellate responsible for polyether production

A

Gambierdus toxicus

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15
Q

Use of halichondrin

A

Antitumor

16
Q

Modified deriv. of halichondrin; for treatment of advanced breast cancer

A

Eribulin

17
Q

Potent inhibitor of squalene synthase

A

Zaragosic acid

18
Q

Steroid precursor of zaragosic acid

A

Presqualene