limbic system

Question 1

what is the limbic system

Answer 1

separates the neocortex from diencephalon

Question 2

Papez circuit

Answer 2

1. hippocampus (learning and memory) via fornix to the 2. hypothalamus (mammillary bodies) via mammillothalamic tract to the 3. thalamus (anterior nuclei) to 4. cingulate gyrus and then back to 1.hippocampus

Question 3

hippocampus

Answer 3

learning and memory!

amygdala to hippocampus

lesion: HM seizures, maintained a short term memroy, but no anterograde declarative memory

Question 4

hypothalamus

Answer 4

Five Fs (feeding, fighting, fleeing, furnace, effing)

mammillary bodies(Wernike- korsakoffs syndrome thyamine deficiency - major memory issues)

Paraventricular nucleus (PVN): head of HPA axis)- stress axis in

PVN is what realeases the Corticotropin releasing hormone–> ACTH from pituitary–> cortisol from adrenals

Question 5

anterior thalamic nuclei

Answer 5

Episodic memory (whats the capital of the USA)

Question 6

cingulate cortex

Answer 6

anterior (ACC): emotional assessment, learning and regulation

Posterior (PCC): balance internal vs external focusddd

Question 7

bilateral temporal lobectomy

Answer 7

visual agnosia (cant visualize objects)
hyperphagia (escessive appetite)
hypersexuality
emotional blunting 
LACK OF FEAR

Question 8

amygdala

Answer 8

evolutionary conserved critical subdivisions

ceA- efferent tracts
basolateral- major player to neocortex and the big input
medial MeA- olfactory input fear conditioning

thalamus to BLA via striaterminalis , ceA to many primary cortices

Question 9

fear and the amygdala

Answer 9

Joseph LeDoux (present) fear conditioning in CeA

Question 10

Papez circuit updated

Answer 10

add amygdala to hippocampus and PFC and association cortices

Question 11

prefrontal cortex

Answer 11

Functions: attention, cognition, short term memory, mayber where feelings are generated

mammalian homology