Limbic System Flashcards

1
Q

Limbic system - does what

A

emotions, feelings, mood, motivation

motivation has a lot to do with our patterns of movement

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2
Q

Which cortex is particularly important for reward and motivation

A

Orbitofrontal cortex

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3
Q

Limbic system - functional lobe - where is it

A

Medial surface of each hemisphere - upper boundary is the cingulate sulcus

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4
Q

Primary limbic cortex includes

A

Cingulate gyrus
Parahippocampal gyrus
Uncus
ACC

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5
Q

ACC is extremely important for

A

depression and mood

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6
Q

Limbic association includes what

A
Parts of the thalamus
hippocampus
amygdala
hypothalamus
insula
parts of basal forebrain
orbitofrontal cortex
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7
Q

Hippocampus is located

A

Mediotemporal

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8
Q

Cingulate gyrus sits above what

A

corpus callosum

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9
Q

amygdala sits where

A

next to hippocampus

these are all deep and medial structures

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10
Q

Emotions =

A

physiological responses to negative/positive stimuli

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11
Q

Emotions - Brain

A

Changes in arousal level, cognitive functions, attention, memory

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12
Q

Emotions - Body

A

Endocrine, autonomic, musculoskeletal responses (freezing, flight, expression of fear or surprise through facial expression)

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13
Q

Emotions are

A

automatic, largely unconscious behavioral and cognitive responses triggered when the brain detects a pos/neg stimulus

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14
Q

Feelings =

A

Conscious experiences, conscious perception of those physiological emotional responses
Afraid, sad, angry
We are afraid because we run!

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15
Q

Neural control of emotional responses to external stimuli - Emotional stimuli to sensory systems activates what

A
Emotion systems (amygdala) and then if it is salient it is activated 
Amygdala acts as decision making body
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16
Q

Neural control of emotional responses to external stimuli - Emotional stimuli to sensory systems activates emotional system (amy) and then salient so gets activated and then what

A

Hypothalamus and brainstem
Spinal cord and autonomic ganglia
Effector cells
And then you get the emotional response

17
Q

Emotion - Amygdala - Animal study

A

Classic conditioning with the mouse - tone (conditioned stimulus) and shock (unconditioned)
Even without shock and just heard the tone, the stress response is still triggered
There is associated learning going on

18
Q

Emotion - Amygdala - Human study

A

Human lesions of amygdala and person will fail to undergo fear conditioning
Their emotional learning is poor and they do not recognize facial expressions of fear

19
Q

Other brain areas that contribute to emotional processing

A

Cortex - ACC, prefrontal, orbitofrontal

20
Q

Other brain areas that contribute to emotional processing - prefrontal is particularly important for

A

social emotions - complex feelings associated with social interactions - empathy, pride, embarassement, guilt

21
Q

Other brain areas that contribute to emotional processing - damage to prefrontal cortex (TBI) - leads to

A

impaired social relations and impaired social emotion processing

22
Q

Other brain areas that contribute to emotional processing - human lesion to orbitofrontal

A

Behavioral control, say things that are socially unacceptable, impulsive, outbursts of physical and verbal aggression, lack of emotion about the outcome

23
Q

Other brain areas that contribute to emotional processing - lesion to ACC

A

Major depression, bipolar disorders

24
Q

Monkey study with orbitofrontal cortex showed what

A

the orbitofrontal cortex codes for preference, reward, and motivation

25
Q

ACC activation in someone who is depressed

A

Lower levels of ACC activation in someone who is depressed

26
Q

ACC activation - normal people with no hx of depression but have them recall sad events and what do you see

A

ACC lights up (and it does not with thinking about positive events)

27
Q

ACC has association with what kind of stimuli

A

negative

28
Q

What else are they doing in research with the ACC

A

Inc activity in ACC predicted responsiveness to tx with antidepressant
drugs
Person who is depressed and has a certain level of activity of the ACC may respond better to drugs than someone who does not have that activation