Limb Development + inheritance patterns Flashcards
A mutation of Hox 13 could cause
Syndactyly
Limb buds arise from
Apical epidermal ridges
Muscles of head, SKMM, skeleton, and dermis arise from
Paraxial mesoderm
Epidermis, hair, nails, cutaneous, maxillary arise form
Ectoderm
AERR forms at
FGF10 and secretes FGF 8, FGF 4
What supplies the blood in limb development
Primary axial artery
What is ectrocdactyly
Lobster claw
What is meromelia
Flapper baby
What is sirenomelia
Mermaid
Indicator for autosomal recessive
Not seen in every generation
Xeroderma pigmentosum is what disorder
Auto recessive
Indicator for auto Dominant
Two affected can have unaffected children, 50 percent
Huntington’s disease is what condition
Auto dominant
Indicator for x linked recessive ve
Primarily affects males
Hemophilia A is what disorder
X linked recessive