Genome, Replicaiton, Mutation, Repair Flashcards
1
Q
What does SSBP prevent
A
Reannealing
2
Q
Which polymerase replaces primers
A
Pol 1
3
Q
What does PCNA do
A
Keeps polymerase bound
4
Q
BER pathway
A
MYH, AP nuclease, PARP
5
Q
MM Pathway
A
MSH, MLH
6
Q
What is Lynch syndrome associated with
A
MM
MLH-PMS 2
MSH2-MSH6
7
Q
Types of NER
A
GG and TC
8
Q
Pathway of NHEJ
A
Ku 70, Ku80, Artemis
9
Q
Pathway of homologous recombination
A
MRN, ATM, BRCA 1, PALB, BRCA2
10
Q
Which can cause a loss of heterozygosity
A
Homologous recombination
