Lilley Chapter 27: Coagulation Modifier Drugs Flashcards

1
Q

A female patient has been prescribed warfarin in addition to a heparin infusion. What is the reason for her receiving two anticoagulants?

a. The oral and injection forms work synergistically.
b. The combination of heparin and an oral anticoagulant results in fewer adverse effects than heparin used alone.
c. Oral anticoagulants are used to reach an adequate level of anticoagulation when heparin alone is unable to do so.
d. When oral anticoagulants are prescribed, heparin is often used to initiate therapy until laboratory tests indicate an adequate therapeutic response.

A

d. When oral anticoagulants are prescribed, heparin is often used to initiate therapy until laboratory tests indicate an adequate therapeutic response.

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2
Q

Which is a true statement about dipyridamole?

a. It has anti-inflammatory and antipyretic properties.
b. It has analgesic properties and antithrombotic effects.
c. It is useful for reducing the risk of fatal and nonfatal thrombotic stroke.
d. It is used as an adjunct to warfarin the prevention of postoperative thromboembolic complications.

A

d. It is used as an adjunct to warfarin the prevention of postoperative thromboembolic complications.

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3
Q

What is the most frequent adverse effect of thrombolytic therapy?

a. Dysrhythmia
b. Nausea and vomiting
c. Anaphylactic reactions
d. Internal and superficial bleeding

A

d. Internal and superficial bleeding

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4
Q

What is the recommended antidote for warfarin toxicity?

a. Vitamin E
b. Vitamin K
c. Protamine sulphate
d. Potassium phosphate

A

b. Vitamin K

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5
Q

The nurse is administering heparin subcutaneously. Which instruction for doing this is correct?

a. Aspirate before injecting
b. Massage site after injection
c. Apply heat to the injection site.
d. Use a new, sterile 1.5cm to 28 gauge needle for the injection.

A

d. Use a new, sterile 1.5cm to 28 gauge needle for the injection.

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6
Q

Which statement is true for the patient receiving long-term therapy with aspirin?

a. Aspirin should be taken on an empty stomach to ensure maximal absorption.
b. Bleeding tendencies are not of much concern to those taking aspirin therapy.
c. Laboratory studies should be done to monitor liver, renal, and clotting functions.
d. Development of a rash is expected and does not warrant discontinuing the medication.

A

c. Laboratory studies should be done to monitor liver, renal, and clotting functions.

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7
Q

A male patient will be receiving streptokinase as part of the treatment of acute myocardial infarction. He asks why he is being prescribed this drug. the nurse’s best response is to tell him that the drug is being prescribed to:

a. Relieve chest pain
b. Prevent further clot formation
c. Dissolve the clot in his coronary artery
d. Control bleeding in the coronary microcirculation

A

c. Dissolve the clot in his coronary artery

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8
Q

Which laboratory study is used to monitor the therapeutic effects of heparin?

a. Prothrombin time
b. Activated partial thromboplastin time (aPTT)
c. Vitamin K
d. Hematocrit

A

b. Activated partial thromboplastin time (aPTT)

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9
Q

A patient has started on anticoagulant drugs. What is the primary goal of this therapy>

a. To prevent thrombus formation
b. To dissolve an existing thrombus
c. To stabilize an existing thrombus
d. To prevent the thrombus from becoming an embolus

A

a. To prevent thrombus formation

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10
Q

A patient is taking anticoagulant therapy. Which natural health product should the patient avoid taking?

a. Valerian
b. Ginkgo
c. St. John’s wort
d. Saw palmetto

A

b. Ginkgo

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11
Q

A patient who is taking warfarin therapy has a headache and wants to take a pain reliever. Which action is recommended?

a. Taking aspirin tablets
b. Taking ibuprofen or NSAID
c. Taking acetaminophen
d. Calling the physician’s office an order for an opioid

A

c. Taking acetaminophen

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12
Q

Which laboratory study is used to monitor the therapeutic effects of warfarin?

a. International normalized ratio (INR)
b. aPTT
c. Vitamin K
d. Hematocrit

A

a. International normalized ratio (INR)

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13
Q

Which drug is the recommended antidote for heparin toxicity?

a. Vitamin E
b. Vitamin K
c. Protamine sulphate
d. Potassium phosphate

A

c. Protamine sulphate

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