Life Science, ATI Manual Flashcards
Macromolecules are what
carbohydrates, nucleic acids, proteins, lipids
anabolic vs catabolic reactions
anabolic REQUIRES energy (build into bigger molecules), catabolic RELEASE energy (large molecules broken down into smaller)
Think “RELEASE THE CAT!”
endothermic vs exothermic reactions
both are chemical reactions
“endo” - absorb heat
“exo” - release heat
main source of energy (macromolecule)
carbohydrate
carbohydrates broken down into _______.
GLUCOSE (or the oxidation of carb)
glucose broken down via __________.
GLYCOLYSIS (respiration/fermentation)
CH₂0 is an example of what macromolecule
carbohydrate (look at chemical structure - carbon, hydrogen, oxygen)
name 3 examples of monosaccharides. also, what are monosaccharides?
they are simple sugars. disaccharides are also simple sugars, just with two monomers of sugar instead of one.
examples: glucose, fructose, galactose
monosaccharides = one (mono) carbon for every water molecule
what’s a monomer
a small molecule. can be linked together to make something even bigger.
many monomers make up a _________.
polymer!
a compound of large molecules - repeating monomers.
which macromolecule is NOT a polymer?
lipids!
carbs, proteins, and nucleic acids are polymers.
lipids are hydrophilic or phobic?
hydrophobic!
don’t mix (or bond) well with water
what kind of bonds do lipids have in abundance?
C-H bonds… similar to “hydrocarbons” in this way. hydrocarbon is how it looks… look at the spelling… it is a substance consisting only of hydrogen and carbon.
role of lipids? give a few examples.
energy storage and structural functions
examples: fats, phospholipids, steroids, waxes.
made of long chains of fatty acids… also what is a fatty acid?
FATS (fats are triglycerides) tri - meaning 3… made of long chains of fatty acids, which are 3 fatty acids bound to a glycerol.
fatty acids are chains with reduced carbon at one end and a carboxylic acid group at the other.
describe a phospholipid
lipids that have a phosphate group!!
NO FATTY ACID
Glyceride is what?
another type of lipid. EXAMPLE?
Fat and oil are examples. Formed from fatty acids + glycerol.
Glycerol is a type of alcohol.
Glycerol is a type of
ALCOHOL
macromolecules formed from amino acids?
PROTEINS! aka POLYPEPTIDES - which are many peptides linked together. Result of a certain type of reaction.
A peptide is a compound of 2 or more amino acids.
Peptide reactions are a result of
CONDENSATION REACTION. Results in a LOSS of water when two molecules are joined together.
Think when rain falls from a cloud, the result is condensation, or the cloud’s LOSS of water.
Hydrolysis reaction
opposite of condensation reaction. water is ADDED to the reaction.
Peptide is a
compound of 2 or more amino acids.
How are amino acids formed?
formed by the partial hydrolysis of protein, which forms an amide bond - this PARTIAL hydrolysis involves an amine group and a carboxylic acid.
When talking about the macromolecule PROTEIN… chemically, what determines the properties of the protein
the “R” group.
Made of several components…
-COOH which is the carboxylic acid
-NH₂ which is the amine group
- a central carbon atom with attached hydrogen
- an attached “R” group
what synthesizes and stores RNA
NUCLEOLUS
Ribosome do what
synthesize proteins from amino acids. Can be thousands. Some are mobile, some are embedded in Rough ER.
Golgi apparatus (complex)
synthesizes proteins and other materials headed OUTSIDE of the cell.
Vacuoles
Sacs for storage, digestion, waste removal. Animal and plant cells both have.
Think: “vacuum” what does a vacuum store
Endoplasmic reticulum
2 types
Rough ER: rough is actually “rough”, think bumpy, it has ribosomes on it.
Smooth ER: does not have ribosomes on surface. Network that comprises the transport system of a cell.
Mitochondrion
Some cells have few, some have many. FUNCTION: GENERATE ATP, also involved in CELL GROWTH and DEATH.
*Contain their OWN DNA (wow, separate from DNA in nucleus)
4 in-depth functions mitochondria
cell energy, cell signaling, cellular differentiation, cell cycle/growth regulation.
AEROBIC RESPIRATION OCCURS HERE!!
Involved in mitosis and cell cycle
Centrosome
Involved in cellular division
Centrioles
know difference between mitosis and meiosis
IN MEIOSIS, PHASES HAPPEN TWICE! Meiosis encourages genetic diversity.
Result at end of meiosis 2 is four daughter cells with different sets of chromosomes. Daughter cells are haploid, which means they contain half the genetic material of parent cell. “Haploid sounds like half”
polypeptides are what
proteins - they’re many peptides linked together… proteins are formed from amino acids.
what do enzymes do
accelerate the speed at which specific reactions approach equilibrium. they’re never USED UP … they can be used AGAIN and AGAIN. Constant source of energy accelerant for cells
reactants aka
SUBSTRATES… the key in the lock analogy - the substrate has to be a match for the active site on the enzyme
Nucleic acids are what? composed of what?
nucleic acids are macromolecules composed of NUCLEOTIDES.
Hydrolysis is a reaction in which what happens?
water is broken down into hydrogen cations (H or H+) and hydroxide anions (OH or OH-) used to break down shorter strings of RNA/DNA (nucleic acids broken down by enzymes) into oligonucleotides. smallest unit is called nucleosides.
fancy name for DNA/RNA
macromolecular nucleic acid polymers
how are RNA/DNA formed? break it down
formed from nucleotides, which are monomeric units joined by phosphodiester bonds.
To replicate DNA - cells require energy in the form of
ATP to synthesize nucleotides for DNA and amino acids for proteins.
these store info and energy and are also important catalysts (not enzymes)
Nucleic acids
example: RNA catalyzes transfer of DNA genetic info INTO protein coded info.
this is an RNA nucleotide
ATP
what is used to form the nucleic acids?
NUCLEOTIDES
Nucleotides are made of a five-carbon sugar and what else?
five-carbon sugar such as ribose or deoxyribose, a nitrogenous base, and one or more phosphates.
Nuclotides with more than one phosphate have this special ability
CAN STORE ENERGY IN THEIR BONDS
Chromosomes consist of these units of genetic info
GENES.
Genes are made up of DNA, a nucleic acid located in cell nucleus. (also found in mitochondria).
DNA structure
consists of nucleotides - consist of a five-carbon sugar (pentose), a phosphate group, and a nitrogenous base.
Two bases pair up to form the rungs of ladder (double helix is twisted ladder shape)
Hydrogen bonds attach the bases to each other which can easily be dismantled so REPLICATION can occur.
4 types of _____ bases (DNA)
nitrogenous bases: adenine (A), guanine (G), cytosine (C), thymine (T). There are about 3 billion bases in human DNA, they’re mostly the same in everyone, but their order is different. The ORDER of these bases that creates diversity!
pairs with DNA
A –> T
C –> G
5 DNA bases in DNA and RNA are categorized as
PYRIMIDINE or PURINE
PYRMIDINE bases are
cytosine, thymine, and uracil.
six-sided, single ring shape
PURINE bases are
guanine and adenine
“GA” think… remember “GA” as in GA-GA… because a “Baby is ‘PURE’”
two attached rings, one has 5 sides and other has 6 sides.
tip: if it ends in “OSINE” its formed from a
PURINE base.
tip: if it ends in “IDINE” its formed from a
PYRMIDINE base.
what’s a codon
groups of 3 nucleotides on the messenger RNA, looks like 3 rungs on a ladder.
a CODON has the “CODE” for a single amino acid.
64 codons, 20 amino acids.
Examples: AAA or AAG (both code for lysine).
how do you read this:
AAAUCUUCGU
read in groups of 3. look for the start and stop codon.
what is the start codon
AUG
what are the stop codons
UAA, UGA, UAG (all start with U)
When replication starts, what happens to the DNA?
It unwinds.
This controls DNA replication
enzymes, specifically HELICASE
“origin of replication” is used to refer what?
where the splitting “ORIGINATES” or starts when hydrogen bonds begin to be split during DNA replication
“replication fork”
the portion of the DNA that is unwound to be replicated
Each strand of DNA is TRANSCRIBED by
an mRNA. It copies the DNA onto itself, base by base in a complementary manner. Exception is that URACIL REPLACES THYMINE.
URACIL replaces what? during DNA replication
THYMINE
mRNA function. also there are different types of RNA, what are they?
acts as a helper to DNA and carries out a number of other functions.
mRNA - carries copy of a strand of DNA and transports it rom nucleus to the cytoplasm
tRNA - helps in translation process (what “t” stands for)
rRNA - hasn’t changed much. used to study relationships of organisms.
what is transcription?
process in which RNA polymerase copies DNA into RNA.
what is translation?
process whereby ribosomes use transcribed RNA to put together the needed protein.
Big difference between DNA and RNA (structure wise)
RNA has ribose sugar while
DNA has deoxyribose sugar
bases for RNA are A,G,C, and U
Uracil only found in RNA
Thymine only found in DNA
RNA = single strand (one “backbone”)
DNA = two strands
RNA supports the functions carried out by DNA