LGBT Flashcards

1
Q

Sex vs Gender

A
  • Sex: assigned based on external genitalia
  • Gender: assigned based on an internal sense of self and how one fits into society
  • Gender non-binary: doesn’t fit as male or female, on spectrum
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2
Q

Queer

A
  • Term used to express fluid identities and orientations

- May have a negative connotation for some LGBT members

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3
Q

Health Disparities in LGBT

A
  • Higher rates of depression/anxiety/suicide
  • Higher rates of homelessness
  • Higher rates of violence victimization
  • Lower rates of mammography and Pap smear
  • Higher rates of smoking/substance abuse
  • Higher rates if HIV and other sexually transmitted diseases
  • Higher rates of unhealthy weight control/perception
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4
Q

Goals of LGBT Awareness/Competency

A
  • Improve healthcare to LGBT patients
  • Decrease LGBT health disparities
  • Improve outreach/education on health risks of LGBT people
  • Create an LGBT affirming environment for healthcare professionals and patients
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5
Q

Implicit/Privilege

A
  • Implicit: individual feeling that we are unaware of or mistaken about their nature (own personal preferences/aversions)
  • Implicit bias: out attitude towards people and associated stereotypes with them without conscious knowledge
  • Privilege: advantages granted to a particular person or group
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6
Q

Gender Pronouns

A
  • Make sure patient is still using pronouns that you have listed periodically
  • Some identify as a gender but aren’t ready to use the pronouns for that gender yet
  • EMR/systems of care can help to determine sex assigned at birth and affirmed gender
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7
Q

Informed Consent Model

A
  1. Review: Gender history and experience, collaborate with behavioral health
  2. Set Goals: gender goals, will HT meet the goals, greater dysphoria?
  3. Consent: obtain consent
  4. Assess: Safety concerns, housing, work, transportation
  5. Monitor: order screening labs, hormones, CBC, fasting lipids, LFTs, STI, HIV, etc.
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8
Q

Treatments for Gender Dysphoria

A
  • Social transition
  • Psychotherapy
  • Pharmacologic therapy
  • Surgery: gender confirmation
  • Voice training
  • Electrolysis
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9
Q

Individualizing Treatment

A
  • Degree of transition: binary female, androgynous, feminine spectrum
  • Erections: eliminate or maintain
  • Surgery: Some patients may take hormones to prepare for surgery while others may not want surgery at all
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10
Q

Feminizing Hormone Therapy

A
  • General approach: estrogen (preferably beta-estradiol) with anti androgen
  • Anti-androgen: spironolactone or GnRH analog
  • Spironolactone inhibits testosterone synthesis and androgen binding to receptor (higher than CV disease)
  • GnRH analog: block GnRH receptor to stop follicle stimulating hormone and luteinizing hormone
  • Aim: 100-200 pg/mL for estrogen, <55 ng/dL for testosterone
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11
Q

Estrogen SE

A
  • Hot flashes
  • Mood swings
  • Migraines
  • Weight gain
  • VTE: oral ethinyl estradiol
  • HyperTGA
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12
Q

Reducing VTE Risk

A
  • Use 17-beta estradiol (preferably patches)
  • Avoid first pass metabolism and tobacco use
  • Avoid combination of progesterone with estrogen
  • Do not exceed estrogen levels above physiologic range of cis-females
  • Low dose aspirin?
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13
Q

Estradiol CI

A
  • VTE related to underlying hypercoagulable state
  • Estrogen sensitive neoplasm
  • End-stage liver disease
  • Informed consent process should be done with patients with these risk factors
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14
Q

Masculinizing Hormone Therapy

A
  • Goals: develop male secondary sex characteristics, suppress/minimize female secondary characteristics
  • General approach: Testosterone monotherapy
  • Goal levels: 400-700ng/dL between injections
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15
Q

SE/CI of Testosterone

A
  • Polycythemia: transdermal has less
  • Weight gain
  • Mood lability
  • Increased sex drive
  • Infertility
  • Lower HDL and elevated TGA
  • CI: Pregnancy
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16
Q

Risk vs Benefit

A

Risks

  • VTE
  • Weight gain
  • Sexual dysfunction
  • Infertility
  • Acne
  • Lipid changes

Benefits
-Preventing suicide