Levodopa Flashcards
1
Q
MoA
A
Precursor to Dopamine
Metabolised by dopa decarboxylase to increase DA levels
2
Q
Indications
A
Parkinson’s Disease
1st Line Early
3
Q
ADR
A
Confusion, hallucinations, psychosis
Long-term: Motor fluctuations
(e.g. on/off phenomenon), dyskinesia
Postural hypotension
4
Q
Prescribing Advice
A
Administration with dopa carboxylase inhibitor
e.g. Carbidopa to reduce peripheral SEs