Levodopa Flashcards

1
Q

MoA

A

Precursor to Dopamine

Metabolised by dopa decarboxylase to increase DA levels

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2
Q

Indications

A

Parkinson’s Disease

1st Line Early

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3
Q

ADR

A

Confusion, hallucinations, psychosis
Long-term: Motor fluctuations
(e.g. on/off phenomenon), dyskinesia
Postural hypotension

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4
Q

Prescribing Advice

A

Administration with dopa carboxylase inhibitor

e.g. Carbidopa to reduce peripheral SEs

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