Dopamine Agonist Flashcards
1
Q
Examples
A
Ergot = Pergolide, Cabergoline Non-Ergot = Ropinirole, Rotigotine
2
Q
MoA
A
Post-synaptic dopamine receptors
Agonist
Acts as dopamine replacement
3
Q
Indications
A
Parkinson’s Disease (Advance)
1st Line early/late
Treat “off” periods with Levodopa
4
Q
ADR
A
N+V
Drowsiness
Neuropsychiatric problems
Better tolerated than Levodopa
5
Q
Prescribing Advice
A
Non-ergot derivatives preferred
Ergot derivatives: Retroperitoneal, pulmonary pericardial fibrosis
Requires monitoring
