Levetiracetam (Anticonvulsant) Flashcards
What is the brand name of Levetiracetam?
Keppra
What doses of Keppra tablets are available?
150 mg, 500 mg, 750 mg, and 1000 mg
What are the available doses for Keppra extended release tablets?
500 mg and 750 mg
What are the available strengths for oral solution Keppra?
100 mg/mL
What is the available strength for Keppra injection?
100 mg/mL in 5mL vials
What is the indication for Levetiracetam?
It is used for the adjective treatment of partial onset seizures with or without generalization as well as and tonic clonic seizures.
What is the most common dosage for adults 16 it off when using Keppra?
Start with daily dose of 1000 mg, given as twice daily dosing (500 mg twice daily)
What is the mechanism of action of Keppra
The mechanism of action is unknown.
What are the drug interactions of Keppra?
No known clinically significant drug interactions exist.
What are the contraindications of Keppra?
- Contraindicated in patients hypersensitive to any component.
- Use caution and reduced dosages and patient with impaired renal function.
- Therapy should be withdrawn slowly to minimize the potential of triggering a seizure.
- Levitracetam is excreted in human breast milk therefore use caution and nursing mothers.
- Pregnancy Category C
What are the adverse effects of Keppra?
Most common adverse effects include some knowledge, Estonia, infection, and dizziness. It may also cause hostility and nervousness.
What should the RPh tell the patient when counseling them on Levetiracetam?
- May cause dizziness or drowsiness.
- Use care when operating machinery or a mental alertness is required.
- Do not stop therapy unless directed to do so by physician.
- Do not stop therapy abruptly; treatment should be tapered over time.
- If a dose is missed, take as soon as it is remembered then return to normal dosing schedule. Do not double doses.
