Amphetamine w/ Dextroamphetamine Salts (CNS Agent for AHDH)

Question 1

What are the brand names for amphetamine with dextroamphetamine salts?

Answer 1

Adderall, Adderall XR

Question 2

What are the strengths of tablets available for Adderall?

Answer 2

5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg

Question 3

What are the strengths of extended release capsules available of Adderall?

Answer 3

5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg

Question 4

What dose of Adderall is used for the treatment of symptoms of narcolepsy?

Answer 4

Usual dose is 5 to 60 mg per day in divided doses

Question 5

What is the recommended dose for adults taking Adderall XR capsules?

Answer 5

The recommended dosage is 20 mg per day

Question 6

What are the recommended dosages for treatment of ADHD with Adderall?

Answer 6

Children (3-5 years old): start with 2.5 mg daily and increase by 2.5 mg a weekly intervals until optimum affect is seen.
Children (>5 years old): start with 5 to 10 mg daily and increase by 5 mg at weekly intervals until optimum affect is seen.

• XR capsules can be substituted for immediate release tablets at the same total daily dose taken once daily.
• XR capsules can be swallowed whole or the capsule carefully opened and the contents sprinkled on apple sauce. The applesauce/drug mixture should be immediately swallowed whole without chewing.

Question 7

What is the mechanism of action for Adderall?

Answer 7

Amphetamines mechanism of action and 80 HD is unknown. In adults it causes CNS stimulation by direct action on adrenergic receptors, releasing norepinephrine from storage sites

Question 8

What are the drug interactions for Adderall?

Answer 8

• Effects may be increased when used with monoamine oxidase inhibitors and furazolidone.
• Urine alkalizing agents (sodium bicarbonate) increase reabsorption while GI alkalizing agents increase absorption.
• May decrease effects of antihypertensives.

Question 9

What are the contraindications for Adderall?

Answer 9

• Contraindicated in advanced arteriosclerosis, cardiovascular disease, moderate hypertension, hypothyroidism, agitated state, glaucoma, and within 14 days of therapy with the monoamine oxidase inhibitors.
• CNS stimulants have a high potential for abuse and dependence.
• Do not use in patients with a known history of drug abuse.
• Use with caution in patients with mild hypertension.
• Pregnancy Category C

Question 10

What are the adverse effects for Adderall?

Answer 10

Restlessness, dizziness, insomnia, euphoria, tremor, headache, palpitations, tachycardia, dry mouth, unpleasant taste, diarrhea, constipation, and anorexia.

Question 11

What should the RPH tell the patient when counseling for Adderall?

Answer 11

• May cause dizziness use caution when performing activities that require coordination.
• Do not exceed prescribed dosage.
• This prescription cannot be refilled.
• Warning this medication may be habit forming.
• If a dose is missed, skip it and return to normal dosing schedule.
• XR capsules can be swallowed whole or the capsule carefully opened & the contents sprinkled on applesauce. The applesauce drug mixture should be immediately swallowed whole without chewing.