Leukocytes--white blood cells Flashcards
what is the shape of the leukocytes?
spherical shape
what are the functions of the leukocytes?
- protection from foreign microorganism
2. remove dead cells and debris
what are the movements of the leukocytes?
- movement in blood
2. movement in ameboid in tissues
why do we want leukocytes to leave out of your blood vessels?
to move through tissue
what are the two classifications of the leukocytes?
- granulocytes
2. agranulocytes
what is meant by granulocytes?
they have granules
what are the granulocytes of the leukocytes?
- neutrophils (aka: PMN’s)
- basophils
- eosinophils
what are the agranulocytes of the leukocytes?
- lymphocytes
2. monocytes
what are meant by agranulocyte?
has NO granules
granules are collection of what?
collection of enzymes
which granule is most common in the leukocytes?
neutrophils
what is the % of neutrophils in leukocytes?
60-70%
neutrophils have a lining in the inner surface of the nuclear envelope. what is the name of this lining?
heterochromatin
the nucleus in neutrophils has how many lobes?
2-5 lobes (usually 3 lobes)
neutrophils have few of what organelle?
few mitochondria
what are the specific granules neutrophils have?
- alkaline phosphates
- collagenase
- lactoferrin
- 2/3’s of cells lysozyme
these are known as what?
collection of enzymes
what are the deep reddish purple granules in neutrophils?
azurophilic granules
what are azurophilic granules?
primary lysosome
why do neutrophils use these different kinds of enzymes?
to break down and kill foreign substances or to clean up debris
neutrophils are known to be the first what?
first to arrive at injury or inflammation; first sign of defense
what is the life of neutrophils?
short half-life, 1 to 4 days
where are neutrophils formed?
medullary formation
what are the 4 compartments in the neutrophils?
- medullary storage
- circulating “patrolling”
- marginating (temporary excluded from the circulatory)
- connective tissue
summary of neutrophils
formed in the medullary ....stays in the bone ....circulates in the blood ....can get out of the blood and ....wonder around in the connective tissues
what do you call the process in which PMN’s enter circulation from connective tissue?
Diapedesis
what is the function of the diapedesis?
phagocytosis (engulfing and then digesting of solid waste or foreign material by cell)
presence of what, is in response to stimuli and NOT created by increase production?
presence of PMN’s
define stimuli
muscle activity, epinephrine release, bacterial infection
what should you remember about Neutrophils?
they are the FIRST sign of defense, the first cell that shows up at the sight of infection or inflammation
