leukocyte extravasation Flashcards

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1
Q

Rolling

A

Vasucluature E-selectin, P selectin

Leukocyte sialyl-lewis

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2
Q

Tight binding

A

Vasculature ICAM-1

Leukocyte LFA -1 (integrin)

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3
Q

Diapedesis - leukocyte travles between endothelial cells and exit blood vessel

A

Vasculature PECAM-1

Leukocyte PECAM-1

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4
Q

Migration - leukocyte travels through interstitium to site of injury or infection guided by chemotactic signals

A

C5a, IL-8, LTB4 and kallikrein

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