Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HEMA311 > Leukocyte Disorders 2 > Flashcards

Leukocyte Disorders 2 Flashcards

1
Q

generalized neoplastic proliferation or
accumulation of leukopoietic cells with or without
involvement of the peripheral blood

A

leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

group of malignant disorders affecting blood and
blood forming tissue of the bone marrow, lymph system and spleen

A

leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the most common form of leukemia in children
characterized by a rapid increase in the numbers of immature blood cells

A

acute leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

characterized by the excessive
build-up of relatively mature, but
still abnormal, white blood cells

A

chronic leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

the predominant cells are all cells coming from
common myeloid progenitors

A

Granulocytic or Myelocytic Leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

common lymphoid progenitors

A

Lymphocytic/Lymphoid Leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

presence of immature or abnormal cells with WBC count greater than 15 x 10⁹/L

A

leukemic leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

with immature or abnormal cells in peripheral
blood and with WBC count less than 15 x 10⁹/L

A

SUBLEUKEMIC LEUKEMIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

with no immature cells in the peripheral blood and with WBC count less than 15 x 10⁹/L

A

ALEUKEMIC LEUKEMIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

a type of myeloblastic leukemia
malignant green colored tumor of myeloid cases

formation of tumors originating from periosteum, especially of skull, orbits, nasal sinuses, ribs and vertebrae

A

chloroma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a focal malignant tumor
composed of myeloblast or
early myeloid precursors
occurring outside of the
bone marrow

A

MYELOBLASTOMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

cancer of plasma cells

A

myeloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

proliferation of one of
the cell types of the
lymphopoietic reticular
tissue

A

lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

is a reactive but excessive leukocytosis
characterized by the presence of immature cells in the peripheral blood

increase in the total of leukocyte count in which
mimics leukemia

A

leukamoid reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

is a neoplastic clonal MPD that commonly manifests with panmyelosis in the bone marrow and increases in RBC, granulocytes, and platelets in the peripheral blood

A

polycythemia vera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

presence of JAK 2 (janus kinase 2)
 JAK 2 is associated with bone
marrow disorder caused by the
production of too many blood
cells

A

polycythemia vera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

treatment for polycythemia vera that prevents thrombosis

A

aspirin

18
Q

given to a px with high risk for polycythemia

A

hydroxyurea

19
Q

classified as a MPD in which the proliferation of an abnormal type of BM stem cell results in fibrosis, or the replacement of the marrow with collagenous connective tissue fibers

A

Myelofibrosis

20
Q

treatment for myelofibrosis

A

Androgen theraphy
› Prednisone
› Danazol
› Splenomegaly – hydroxyurea

21
Q

Characterized by autonomous proliferation of the
megakaryocytic cell lines.
 Thrombocytosis is present without a reactive
cause.

A

thrombocythemia

22
Q

treatment for thrombocytopenia

A

Busulfan in older patients
› Low dose aspirin to prevent thrombosis
› - Hydroxyurea theraphy

23
Q

a MPD arising as a clonal process from a
pluripotential stem cell
 begins with a chronic clinical phase that
progresses to an accelerated phase in 3 to 4 years and often terminates as an acute leukemia

A

chronic myelogenous leukemia

24
Q

a characteristic feature present in proliferating
hematopoietic cells is the Philadelphia chromosome
 has overproduction of myeloid cellulite that
results in preponderance of immature cells in the
neutrophilic line

A

chronic myelogenous leukemia

25
Q

Can mimic neutrophilic glucamoid
reaction

A

chronic myelogenous leukemia

26
Q

treatment for chronic myelogenous leukemia

A

Busulfan
› Bone marrow stem cell transplantation

27
Q

group of clonal disorder of neoplastic
pluripotential stem cells characterized by a decrease
in one or more types of peripheral blood cells due to
abnormal maturation in the bone marrow

A

Myelodysplastic syndrome

28
Q

represent a group of neoplastic conditions
originating from cells of the lymphoreticular system

A

LYMPHOPROLIFERATIVE DISORDERS

29
Q

composed of small B-lymphocytes
with abundant cytoplasm and fine
(hairy) cytoplasmic projections

A

HAIRY CELL
LEUKEMIA

30
Q

also known as Alibert-Bazin
syndrome
 the most common form of
cutaneous T-cell lymphoma
 is a lymphoreticular neoplasm
primarily involving the skin

A

MYCOSIS
FUNGOIDES

31
Q

a malignant disorder characterized
by painless, progressive enlargement
of lymphoid tissue
 Hallmark is a large binucleated or
multinucleated cell with each nucleus
bearing a very large nucleolus (Reed Sternberg Cell)

A

HODGKIN’S
DISEASE

32
Q

Owl’s eye appearance or popcorn cells

A

Reed-strenberg cell

33
Q

Nodular lymphocyte-predominant
Hodgkin lymphoma
 is a B cell neoplasm composed of
relatively rare neoplastic cells
scattered within the nodules of
reactive lymphocytes
 no reed-sternberg cells

A

NONHODGKIN’S
DISEASE

34
Q

other names:
Plasmatocytoma,
Kohler’s Disease
 is a neoplasmic
proliferation of
morphologically
abnormal plasma cells
primarily occurring in the
BM either in nodules or
diffusely.

A

MULTIPLE MYELOMA

35
Q

is an uncommon
condition which behaves
as a slowly progressive
lymphoma
 is proliferation of cells
which produce a
monoclonal IgM
paraprotein

A

WALDENSTROM’S
MACROGLOBULINEMIA

36
Q

Other name: Glandular Fever, Pfeiffer’s
Disease, Kissing Disease (commonly called)

A

INFECTIOUS MONONUCLEOSIS

37
Q

T cells reacting against B lymphocytes
infected with Epstein-Barr (EB) virus

A

INFECTIOUS MONONUCLEOSIS

38
Q

represent a group of diseases with abnormal
proliferation of mesenchymal cells that are
closely related to phagocytic histiocytes and to
fat cells
 due to inborn errors in metabolism
genetically transmitted

A

HISTIOCYTOSES/ STORAGE DISEASE

39
Q

is a collagen disease which affects women
most commonly
 characterized by skin rash, arthralgia, fever,
renal, cardiac and vascular lesions, anemia,
leukopenia, and thrombocytopenia

A

SYSTEMIC LUPUS ERYTHEMATOSUS

40
Q

3 TYPES OF ANTIBODY of SLE

A

Anti-DNP
Anti-DNA
Anti-Nuclear

41
Q

ACQUIRED IMMUNODEFICIENCY
SYNDROME

A

a disorder secondary to an infection with the
human immunodefficiency virus (HIV)

42
Q

a RNA retrovirus that is cytotropic for
CD4 positive T cells and macrophages

A

HIV

HEMA311 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions