leukemia Flashcards
1
Q
leukemia of older adults
A
AML
2
Q
leukemia of young children
A
ALL
3
Q
Difference between AML and ALL in presentation
A
- Lymphadenopathy seen in ALL
- Infiltration of the CNS
4
Q
AML or ALL can present with
A
- bone marrow failure symptoms - anemia, pallor, leukopenia, thrombocytopenia, bruising bleeding
Lymphadenopathy ALL
5
Q
Favorite tissue spot for AML infiltration
A
- Gingiva
especially in AML with monocytic characeristics
6
Q
retinal hemorrhage
stroke
resp failure
can be signs of
A
LEUKOSTASIS
7
Q
Treatment for acute PML
A
arsenic and ATRA
8
Q
CML and CLL affect
A
older adults
men> women
CLL more common
9
Q
Splenomegaly - leukocytosis - thembocytosis - basophilia - left shift asymptomatic
A
CML
10
Q
Smudge cells
asymptomatic
lymphocytosis
A
CLL
11
Q
Median survival of CML without treatment
A
3 y
12
Q
Median survival of CLL without treatment
A
10-25 years
13
Q
treatment for CML
CLL
A
TKI
Chemo/rituximab
