LEUCEMIA MIELOIDE CRONICA Flashcards

1
Q

En donde es la Mutación de la LMC

A
  • Cromosoma Philadelphia (9:22)

- BCR-ABL

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2
Q

Que podemos ver en una BH de un Px con LMC

A
  • ANEMIA NORMO-NORMO
  • HB ⬇️
  • HCM ↕️ 27-32
  • VCM ↕️ 80-100
  • Fosfatasa Alcalina ⬇️
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3
Q

Que podemos encontrar en el FROTIS de un Px con LMC

A
  • LEUCOCITOS
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4
Q

Manifestaciones clínicas de la LMC

A
  • Hipermetabolismo
  • Hepatoesplenomegalia
  • Sintomas B
  • Anemia
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5
Q

DX de LMC

A
  • HIBRIDACION DE FLUORESCENCIA
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6
Q

TX de LMC

A
  • IMATIMIB (inhibidor de Tirosincinasa)

- Transplante Alogenico de células troncales

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7
Q

En qué consiste la Fase Acelerada de LMC

A
  • ⬆️ Proliferación de cel inmaduras
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8
Q

En qué consiste la fase BLASTICA de LMC

A
  • > 20% BLASTOS
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9
Q

En qué consiste la fase CRÓNICA de LMC

A
  • < 10% BLASTOS
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10
Q

Tx de elección en Px Embarazada 🤰🏻 con LMC

A
  • HIDROXIUREA
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