Lesson 7: Genetics Flashcards

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1
Q

Genetics

A

the specific study of heredity

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2
Q

Heredity

A

the transfer of genetic traits from parent to offspring

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3
Q

Gregor Mendel

A

father of genetics; discovered both parents contribute and equal amount of genes to their offspring, not a blend;

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4
Q

What species did Mendel work with and why?

A

Garden peas:
● reproduce quickly with lots of offspring
● simple traits (tall/short)
● hermaphrodite (can self/crossbreed

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5
Q

True-Breeding

A

only produce the same offspring

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6
Q

Mendel’s Theory

A

for every trait, an individual has two versions of a gene (allele) that can be dominant or recessive (dominant overpowers recessive)

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7
Q

Homozygous

A

Same alleles for a trait
➜ Homozygous dominant - 2 dominant alleles
➜ Homozygous recessive - 2 recessive alleles

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8
Q

Heterozygous

A

● Heterozygous - 2 different alleles

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9
Q

Genotype

A

pair of alleles for a trait (genes)
Ex. AA, Aa, aa

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10
Q

Phenotype

A

the physical trait (caused by the genotype)
Ex. blonde hair, blue eyes

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11
Q

If you are heterozygous, the dominant allele is expressed in the ___.

A

phenotype

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12
Q

Each trait is represented by a ___.

A

letter
● Caps - dominant
● Lowercase - Recessive

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13
Q

Standard Punnett Square Genotype Ratio

A

Homo-d : Hetero : Homo-r

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14
Q

Standard Punnett Square Phenotype Ratio

A

Dom : Rec

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15
Q

Law of Segregation

A

the members of each pair of alleles separate when gametes form ➜ you only give one of each homologous pair of chromosomes to each gamete

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16
Q

Law of Independent Assortment

A

pairs of alleles separate independently
➜ not true for alleles on the same chromosome

17
Q

Complex traits examples

A

● Alleles can be partially dominant/recessive
● One gene can have more than 2 alleles
● Many genes can impact one trait

18
Q

Complex Patterns of Heredity

A

● Incomplete Dominance
● Codominance
● Multiple alleles
● X-Linked (Sex-Links) Traits
● Polygenic

19
Q

Incomplete Dominance

A

heterozygote is a mix of the parents phenotype (neither is dominant), similar outcome to blending theory

20
Q

Incomplete Dominance Ratios

A

● Genotype - Homo : Hetero : Homo
● Phenotype - Homo : Hetero : Homo
Genotype and Phenotype ratio will be the same

21
Q

Codominance

A

Both alleles are expressed in the phenotype

22
Q

Codominance ratios

A

● Genotype - Homo : Hetero : Homo
● Phenotype - Homo : Hetero : Homo
Genotype and Phenotype ratio will be the same
(Same as incomplete dominance)

23
Q

Difference between Incomplete Dominance and Codominance

A

● Incomplete Dominance:
➜ Red + White = Pink
● Codominance:
➜ Red + White = Red & White

24
Q

Multiple alleles

A

● More than two alleles possible for a trait
● Blood types determined by 3 alleles: A, B i
● Genotype ➜ Phenotype
- AA ➜ A
- BB ➜ B
- AB ➜ AB (universal acceptor)
- Ai ➜ A
- Bi ➜ B
- ii ➜ O (universal donor)

25
Q

Blood type ratios

A

● Genotype - 6 outcomes (AA, BB, AB, Ai, Bi, ii)
● Phenotype - 4 outcomes (A, B, AB O)
*Label ratios

26
Q

Non-standard Types of Inheritance

A
  1. Incomplete Dominance
  2. Codominance
  3. Multiple Alleles
  4. Polygenic - Many genes determine a single trait (can’t solve with a Punnett Square)
27
Q

Environmental factors

A

Your surroundings can influence your phenotype (and in some cases your genotypes)

Ex. Color of an arctic fox in the summer vs. the winter
Ex. Flowers blooming earlier in the spring due to global warming

28
Q

X-Linked (Sex-Linked) Traits

A

● Carried on only the X chromosome and are recessive (Non X-Linked traits are called autosomal)
● Males are more likely to get these traits because they have only one X chromosome (one chance for the healthy allele)

Ex. Color blindness (X^B - normal color vision, X^b - colorblind)

29
Q

X-Linked Ratios

A

● Genotype - 5 outcomes (X^B X^B, X^B X^b, X^b, X^b, X^B Y, X^b Y)
● Phenotype - 4 outcomes (Normal vision female (can be a carrier), colorblind female, normal vision male, colorblind male)
*Label ratios

30
Q

Dihybrid Crosses

A

● Cross 2 traits at once
● Each parent - 4 allele combinations (FOIL)
● Genotype - 9 outcomes
● Phenotype - 4 outcomes
*Don’t need to label but put in order from most dominant to most recessive

31
Q

Pedigree

A

A diagram showing the lineage of a group used to analyze Inheritance

32
Q

Genetic Disorders vs. Chromosomal Disorders

A

● Genetic Disorders:
➜ Can be due to mutations in a single gene or multiple genes
➜ Can involve genetic and environmental factors
● Chromosomal Disorders:
➜ Changes in structure or number of whole chromosomes

33
Q

Why are dominant disorders extremely rare?

A

● An individual who carries even one of the alleles will have the disorder
● If it affects the person before they reproduce, the person will usually die and not reproduce so the mutation would not be passed on
● Many dominant disorders occur later, allowing the person to reproduce

34
Q

Why are recessive disorders found in certain ethnic groups?

A

People in an ethnic group share certain versions of their genes which were passed down from common ancestors.

35
Q

Multi-Factorial Disorder

A

a condition caused by multiple factors