Lesson 6: Skin Disease and Disorders Flashcards
Form of cancer that affects the mitotically active stem cells in the stratum basale of the epidermis, most common of all cancers, found on head, neck, arms, and back, causes are UV rays, radiation, and arsenic, rarely metastasize
Basal cell carcinoma
How does the basal cell carcinoma look like?
start in the stratum basale and usually spread along this boundary, begins to grow towards the surface and become an uneven patch, bump, growth, or scar
Treatments for basal cell carcinoma
Surgery, freezing (cryosurgery), and topical ointments
Cancer that affects the keratinocytes of the stratum spinosum, 2nd most common skin cancer, presents as lesions found on scalp, ears, and hands, more aggressive than basal cell carcinoma, can metastasize
Squamous cell carcinoma
Treatments for squamous cell carcinoma
Surgery and radiation
Cancer characterized by the uncontrolled growth of melanocytes, the pigment-producing cells in the epidermis, most fatal of all skin cancers, highly metastatic
Melanoma
How does melanoma look like?
Resembles a mole, asymmetrical brown and black patches, uneven borders, and raised surface
Treatments for melanoma
Surgical excision, radiation therapy, or chemotherapy
What is the ABCDE mnemonic?
Helps with detection of early-stage melanoma
Asymmetry - two sides are not symmetrical
Borders - the edges are irregular in shape
Color - varied shades of brown or black
Diameter - larger than 6mm (0.24 in)
Evolving - its shape or size has changed
Process by which some tumors produce cells that can mobilize and establish tumors in other organs of the body
Metastasis
Inflammatory condition that occurs in individuals of all ages, an allergic reaction that manifests as dry, itchy patches of skin, accompanied by swelling of the skin, flaking, and in severe cases bleeding, sometimes people have antibodies against allergens in their blood
Eczema
Treatments for eczema
Moisturizers, corticosteroid creams, and immunosuppressants
Clogging of pores, which can lead to infection and inflammation, areas of skin rich in sebaceous glands (face and back), hormones like androgens, stimulate release of sebum, overproduction and accumulation of sebum along with keratin can block hair follicles
Acne
How does acne look like?
Initially white, the sebum when oxidized, turns black. Acne results from infection by acne-causing bacteria, propionibacterium, which can lead to redness and potential scarring