Lesson 1: Anatomy of the Skin Flashcards
The outermost layer of the skin
Epidermis - rich in tough protein called keratin, avascular, waterproof barrier
The layer of skin that lies immediately beneath the epidermis
Dermis - elasticity (resistance to stretching force) and strength (collagen) of skin, supplies epidermis with nutrients, role in thermoregulation
The subcutaneous layer of skin
Hypodermis - not classified as part of the skin, connective tissue that contains fat, blood vessels, and sensory receptors, protective cushion and insulator, anchors skin to underlying bone or muscle
Skin Color pigments
melanin, hemoglobin, and carotene
Produced by melanocytes (located in the bottom layer of epidermis), protects skin and underlying tissue from harmful UV radiation
Melanin
Oxygen-carrying molecule in RBC. When oxygenated, appears red
Hemoglobin
A precursor of Vitamin A and produces yellow to orange color, stored in dermis and subcutaneous layer
Carotene
The skin forms a very effective chemical, biological, and physical barrier.
Protection
The skin plays a significant role in regulating body temperature, as 80% of heat is lost through the skin.
High temp - dilation of arterioles (causes the redness) and sweat glands secrete water, salt, and other substances
Low temp - constriction of arterioles (causes whitish hue)
Thermoregulation
There are a number of sensations that arise from the skin in a process known as _______. These include touch, pressure, vibration, tickle, temperature, and pain.
Cutaneous sensation
Metabolic waste products can be excreted from the body in small quantities via sweat (water and salt, as can ammonia and urea [breakdown of protein]), as well as CO2
Excretion
The synthesis of vitamin D starts in the skin, triggered by ultraviolet light. Forms Vitamin D3 (cholecalciferol) –> liver and kidney transported by blood to turn into calcitriol
Vitamin D synthesis
What are the four main types of cells in the epidermis?
keratinocytes, melanocytes, Langerhans cells, and Merkel cells.
Epidermal cells that produce keratin and another substance that makes the skin waterproof. 90% of the epidermal cells. As they move up, they die and flake away
Keratinocytes
Epidermal cells that produce melanin granules, absorb UV radiation, and are partly responsible for skin color
Melanocytes