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Biochemistry I Final > Lesson 4 - Regulation of Glycolysis > Flashcards

Lesson 4 - Regulation of Glycolysis Flashcards

1
Q

Allosteric and hormonal regulation of Hexokinase and Glucokinase

A

Hexokinase: Allosteric
Stimulant: Glucose ↑
Inhibitor: Glucose-6-Phosphate ↑

Glucokinase: Allosteric
Stimulant: Glucose ↑
Inhibitor: Fructose-6-Phosphate ↑

Hexokinase + Glucokinase: Hormonal
Stimulant: Insulin
Inhibitor: Glucagon

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2
Q

Allosteric and hormonal regulation of Phosphofructokinase-I

A

Allosteric
Stimulant: ADP ↑, Fructose-2,6-Bisphosphate ↑
Inhibitor: ATP ↑, Citrate ↑

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3
Q

Fructose-2,6-Bisphosphate pathway

A
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4
Q

Hormonal regulation of Phosphofructokinase-II and Fructose-2,6-Bisphosphatase

A

Phosphofructokinase-II
Stimulant: Insulin
Inhibitor: Glucagon

Fructose-2,6-Bisphosphatase
Stimulant: Glucagon
Inhibitor: Insulin

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5
Q

Allosteric and hormonal regulation of Pyruvate Kinase

A

Allosteric
Stimulant: Fructose-1,6-Bisphosphate (Feed forward mechanism)
Inhibitor: ATP ↑, Long-chain fatty acids ↑ (beta-ox.), Acetyl-CoA ↑

Hormonal
Stimulant: Insulin
Inhibitor: Glucagon

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Biochemistry I Final (11 decks)

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