Lesson 8 - Glycogenesis Flashcards
1
Q
Where does glycogenesis take place?
A
Liver
100g storage
Muscle
300-400g storage
2
Q
When does glycogenesis take place?
A
Well-fed state, at high blood-glucose levels (physiological hyperglycaemia)
3
Q
Glycogenesis pathway
A
4
Q
What is Glycogenin?
A
Primer for glycogen that uses Tyrosine (Tyr) amino acid
5
Q
What is the function of Glycogen Synthase?
A
Addition of Glucose via UDP-Glucose through α-1,4-glycosidic bonds to Glycogenin
6
Q
What is the function of Branching Enzyme?
A
Cleaves -1,4-glycosidic bonds and synthesizes -1,6-glycosidic bonds
7
Q
Which GLUT transporters are in the liver and muscle?
A
Liver
GLUT-2
Muscle
GLUT-4
8
Q
What is autoglycosylation?
A
Attachment of sugar molecules to itself
