LESSON 18 (Epidermis and Dermis) Flashcards
what does the integumentary system consists of?
skin, hair, nails, sweat glands and sebaceous (oil) glands
what are the 2 regions of the skin? which one is the outermost and the inner? which one is avascular and vascular?
1) epidermis: OUTERMOST and AVASCULAR epithelial tissue
2) dermis: INNER and VASCULAR connective tissue
what is the hypodermis?
- aka SUPERFICIAL FASCIA
- a subcutaneius tissue beneath the skin
- consists of mostly adipose tissue that anchors the skin to underlying muscle
- allows skin to slide over muscle
- acts as a shock absorber and insulator
what are keratinocytes?
- makes up majority of the epidermis cells
- produce a fibrous protective protein called keratin
what are melanocytes?
- epithelial cells that synthesize the pigment melanin and transfer it to kerationocytes to protect the nucleus from UV damage
what are cells?
- tissue-resident macrophages
- a type of white blood cell commonly found in the epidermis
- helps activate the immune system
what are tactile (merkel) cells associated with?
touch and sensory nerve endings
what is Stratum Basale (basal layer)?
- aka Stratum Germinativum due to active mitosis
-the deepest epidermis layer - this layer is firmly attached to the dermis
what does the Stratum Basale consists? and what do they produce?
- a single row of stem cells
- produces 2 daughter cells as it is actively mitotic
what is Stratum Spinosum?
- has 3 to 5 layers of thick cells
- it contains a web-like system of intermediate pre-keratin filaments which is attached to desmosomes
how does keratinocytes appear in the Stratum Spinosum layer?
spikey and prickle cells
what is Stratum Granulosum (granular layer)?
- has 4 to 6 layers
- cells are flattened so the layer is thin
what does Stratum Granulosum accumulate?
- Keratohyaline granules which helps form keratin fibers in upper layers
- and Lamellar granules which slows down the loss of water (as its water-resistant glycolipid)
Why do cells above the Stratum Granulosum die?
because they are too far from the dermal capillaries to survive
where can you find Stratum Lucidum (clear layer)?
- layers that are only found in thick (hairless) skin
ex) palms of hand, soles of feet, surface area of fingers and toes
what does Stratum Lucidum (clear layer) consists of?
- thin, translucent band of 2 to 3 rows of clear, flat, dead keratinocytes