Lesson 1 Flashcards
Who wrote a book on uroscopy in the 5th century BCE?
Hippocrates
Frederik Dekkers discovery in 1694 by boiling urine
Albuminuria
Who develop the methods of quantitating the microscopic sediments?
Thomas Addis
Introduced the concept of urinalysis in 1827
Richard Bright
A metabolic waste product produced in the liver
Urea
Organic substances of urine
Creatinine
Uric acid
Urea
Inorganic components of urine
Chloride
Sodium
Potassium
Urine composition
95% water
5% solutes
Decrease in urine output
Oliguria
Cessation of urine flow
Anuria
Increase in the nocturnal excretion of urine
Nocturia
Increase in daily urine volume
Polyuria
Decreased production of ADH leads to what?
Diabetes insipidus
Decreased insulin and increased glucose leads to what?
Diabetes mellitus
Fluid loss in both diseases is compensated by increased ingestion of water
Polydipsia
The recommended capacity of the urine container
50mL
Volume of the specimen needed for microscopic analysis
12mL
The most routinely used method of preservation
Refrigeration
What changes happen in an unpreserved urine? (Color)
Modified/darkened
Oxidation or reduction of metabolites
What changes happen in an unpreserved urine?
(Clarity)
Decreased
Bacterial growth and precipitated of amorphous material
What changes happen in an unpreserved urine?
(Odor)
Increased
Bacterial multiplication causing breakdown of urea to ammonia
What changes happen in an unpreserved urine?
(pH)
Increased
Breakdown of urea to ammonia by urease-producing bacteria
What changes happen in an unpreserved urine? (Glucose)
Decrease
Glycolysis and bacterial use
What changes happen in an unpreserved urine? (Ketones)
Decreased
Volatilization and bacterial metabolism
What changes happen in an unpreserved urine? (Bilirubin)
Decreased
Exposure to light/ photo oxidation to biliverdin
What changes happen in an unpreserved urine? (Urobilinogen)
Decreased
Oxidation to urobilin
What changes happen in an unpreserved urine? (Nitrite)
Increased
Multiplication of nitratre-reducing bacteria
What changes happen in an unpreserved urine? (Rbc and wbc casts)
Decreased disintegration in dilute alkaline urine
What changes happen in an unpreserved urine? (Bacteria)
Increased
Multiplication