Lesson 1 Flashcards
How would you classify amino acids ?
On basis of
1) Structure
2) Metabolism
3) Nutritional requirements
How would you classify amino acids based on structure? Give examples.
1)Aliphatic
Monoamino monocarboxylic
Simple- Alaline and Glycine
Branched- Valine, Leucine and Isoleucine
Hydroxyamino - Serine and Threonine
Sulphur containing- Methionine and Cysteine
Amide group containing - Aspargine and Glutamine
Monoamino dicarboxylic - Aspartic acid and Glutamic acid
Dibasic monocarboxylic - Arginine and Lysine
2) Aromatic - Phenylalanine and Tyrosine
3) Heterocyclic - Tryptophan and Histodine
4) Imino acid - Proline
5) Derived
Derived amino acid found in proteins
Hydroxy Proline and hydroxy lysine
DAA not seen in proteins - Ornithine , Citruline and Homocysteine
Non alpha amino acids - GABA
How would you classify amino acids based on metabolism and give its examples.
Ketogenic - Leucine
Ketogenic and Glucogenic - Lysine , Isoleucine, Phenylalanine, Tyrosine and Tryptophan
Glucogenic - Remaining 14 amino acids
Classify amino acids on the basis of nutritional requirement and give its examples.
On the basis of nutritional requirements amino acids can be classified into essential and semi essential and non essential amino acids.
Essential - Isoleucine, Leucine, Threonine,
Lysine, Methionine, Phenylalanine, Tryptophan,
and Valine
Semi essential - Histidine and Arginine
Non essential - Remaining 10 amino acids
What do you mean by isoelectric PH
The pH at which the molecule carries no net charge
is known as isoelectric point or isoelectric pH
Which amino acid does not show optical activities?
Glycine
With respect to optical activity that is D and L isomers, which are natural amino acids?
L- amino acids occur commonly in nature and hence are natural amino acids.
Which reaction is essential for synthesis of non essential amino acids?
Transamination reaction
The alpha amino group of amino acid can be transferred
to alpha keto acid to form the corresponding new amino
acid and alpha keto acid
Give some examples of amino acid derivatives of importance.
1) GABA & Dopamine are neurotransmitter
2) Histamine mediater of allergic reaction
3) Thyroxine is important thyroid hormone
4) Cycloserine is antituberculous drug.
5) Histidine involved in buffering activity of proteins.
6) Ornithine and Citruline are important for urea synthesis.
