LES Flashcards

1
Q

Classificação

A

1 Mesangial íntima
2 Mesangial proliferativa
3 Segmentar e focal
4 Difusa
5 Membranosa
6 GESF

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2
Q

LES Mesangial íntima

A
  • OK: endotélio, MB, glomérulo
  • mesangio limitado
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3
Q

LES Mesangial Proliferativa

A
  • OK: GL MB END
  • MESANG PROLIF
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4
Q

LES SEGMENTAR E FOCAL

A
  • SUBENDOTELIAL
  • NECROT/ ESCLEROS SEG FOC
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5
Q

LES DIFUSA

A

NEC/ ESCL DIFUSA

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6
Q

LES MEMBRANOSA

A

Região subepitelial (podócitos)

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7
Q

LES ESCLEROSANTE

A

Inflamação crônica sem classificação de início, com esclerose glomerular

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8
Q

Tratamento LES

A
  • Prot UV
  • Controle HAS, dislipidemia e obesidade
  • Cessar tabagismo
  • Hidroxicloroquina
  • Inunossupressores: corticoide + ciclofosfamida
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9
Q

QUAL A PATOGÊNESE DO COMPROMETIMENTO RENAL DO LES?

A

PROD AUTOANTIC > IMUNOCOMPL > DEPOSIÇÃO GLOMERULAR > INFLAMAÇÃO CRÔNICA

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10
Q

Quais as complicações renais no LES?

A
  • Proteinúria, hemat micro, cil gran
  • Queda função renal, anormalidade tubular, sd nefrotica
  • HAS, Hipercalemia, IRA
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11
Q

Indicação de biópsia

A
  • Alteração sedimento urinário
  • Proteinúria
  • Queda da função renal
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