Leprosy (bacterial) Flashcards

1
Q

Leprosy is also know as

A

Hansen’s Disease

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2
Q

Chronic disease of skin and peripheral nerves

A

Leprosy

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3
Q

Causative agent for Leprosy

A

Mycobacterium Leprae

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4
Q

Mode of transmission of Leprosy

A

Direct prolonged skin to skin contact
Droplet

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5
Q

Early signs of Leprosy
(CLLUMP)

A

Change in skin color
Loss of sensation
Loss of sweating
Ulcers that do not heal
Muscle weakness
Painful and redden eyes

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6
Q

Late signs of Leprosy
(MSCCLE)

A

Madarosis: loss of eyebrows
Sinking of the nose bridge
Contractures: hardening of muscles
Clawing of fingers and toes Lagopthalmos: inability to close eyelids
Enlargement of breast: gynecomastia

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7
Q

Two classifications of Leprosy

A

Paucibacillary
Multibacillary

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8
Q

Characteristics of Paucibacillary

A

Tubercoloid and indeterminate Incubation Period: 1-4 yrs
Not infectious
Few lesions
Few bacilli
6-9 mos treatment

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9
Q

Characteristics of Multibacillary

A

Lepromatous and borderline
Incubation Period: 4-8 yrs
Highly Infectious
More lesions
More bacilli
24-30 mos treatment

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10
Q

Diagnostic test for Leprosy

A

Slit skin smear

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11
Q

Medical management for Leprosy

A

RA 4073 - Domiciliary treatment

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12
Q

Tx for Paucibacillary Leprosy in adults day 1

A

Rifampicin 600mg 1/month
Dapsone 100mg daily

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13
Q

Tx for Multibacillary Leprosy in adults day 1

A

Rifampicin 600mg 1/month
Clofazimine 300mg 1/month
Dapsone 100mg daily

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14
Q

Tx for Paucibacillary Leprosy in adults day 2-28

A

Dapsone 100mg daily
6 blister packs monthly for 6-9 months

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15
Q

Tx for Multibacillary Leprosy in adults day 2-28

A

Dapsone 100mg and Clofazimine 50mg daily
12 blister packs monthly, max: 18 months

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16
Q

Tx for Paucibacillary Leprosy in child day 1

A

Rifampicin 450mg
Dapsone 50mg daily

17
Q

Tx for Multibacillary Leprosy in child day 1

A

Rifampicin 450mg
Clofazimine 150mg
Dapsone 50mg

18
Q

Tx for Paucibacillary Leprosy in child day 2-28

A

Dapsone 50mg daily

19
Q

Tx for Multibacillary Leprosy in child day 2-28

A

Clofazimine 50mg every other day and Dapsone 50mg

20
Q

Prevention for Leprosy

A

Avoid skin-skin contact
BCG vaccine
Personal hygiene
Adequate nutrition

21
Q

Early s/sx of Leprosy

A

Change in skin color
Loss of sensation
Loss of sweating
Ulcers that do not heal
Muscle weakness
Painful and reddened eyes

22
Q

Late s/sx of Leprosy

A

Maderosis - loss of eyebrows
Lagopthalmos - can’t close eyelids
Sinking of nose bridge
Contractures
Clawing of fingers and toes
Gynecomastia