Leprosy

Question 1

Leprosy was founded by who in what year

Answer 1

Founded by gerhard Hansen in 1873

Question 2

What is the microbial physiology of micro bacterium leprae Bacillius

Answer 2

Leprae is an acid fast bacilli
Non sporing non motile aerobic rod shaped Bacillius

It’s is obligately Intracellular

Question 3

When is smear tissue stains, leprae Bacillius stays singly or in compact called

Answer 3

Globi

Question 4

How is leprosy contacted

Answer 4

Leprosy is transferred from person to person in close asscociation by inhaling their infected aerosols

Question 5

Leprosy easily affects what age range

Answer 5

Children

Question 6

Anoda name for leprosy is

Answer 6

Hansen disease

Question 7

Generation time for leprae is

Answer 7

12-13days

Question 8

Incubation time for leprosy is

Answer 8

2-7yrs

Question 9

Can leprosy affects a child in the womb nd why

Answer 9

Leprosy cannot cross the placenta barrier

Question 10

What is the pathogenesis of leprosy

Answer 10

Leprosy is a nerve loving bacteria
It’s attacks nervous system by eating away at the Schwan cells

Question 11

Leprosy is more susceptible in what weather condition

Answer 11

In cold environment
Stays in the pns

Question 12

Leprosy that affects an immunocompetent individual clinically manifests as

Answer 12

Tuberculoid leprosy

Question 13

Which of these is not a clinical presentation of leprosy

Borderline tuberculoid leprosy
Borderline leprosy
Lepratomous leprosy
Borderline borderline leprosy
Tuberculoid leprosy

Answer 13

Borderline leprosy

Question 14

Mention the clinical presentation of leprosy

Question 15

Leprosy that affects immunocompromised individual clinically manifest as

Answer 15

Lepratomous leprosy

Question 16

Leprosy which presents with skin lesions is what type of

Answer 16

Tuberculoid leprosy

Question 17

Leprae Bacillius involving only one peripheral nerve and causes skin blemish is what type of leprosy

Answer 17

Tuberculoid leprosy

Question 18

Leprosy manifesting with skin nodules, lesions to multiple nerve nd damage to other organs is what type of leprosy

Answer 18

Lepratomous leprosy

Question 19

Neural manifestation of Tuberculoid leprosy

Answer 19

Pain
Tingling
Muscle weakness
Paralysis

Question 20

Dermal manifestation of Tuberculoid leprosy

Answer 20

Loss of hair
Loss of sweating
Thickening of nerve

Question 21

Clinical manifestation of Lepratomous leprosy

Answer 21

Nodules in the body nd other organ systems
Presence of nodules
Chronic leg edema

Question 22

Test to check for leprosy include

Answer 22

Lepromin test
Histamine test
Pilocarpine test

Question 23

What is the mechanism of action of a lepromin test

Answer 23

It is an autoclaved suspension of tissue gotten from an infected armadillos

We inject it Intradermally and get either a fernandez (early) or mitsuda (late) reaction

Question 24

A mitsuda reaction is

Answer 24

A late reaction to a lepromin test for leprosy

Question 25

A Fernandez reaction is

Answer 25

An early reaction to a Lepromin test

Question 26

Intermediate clinical manifestation of leprosy include

Answer 26

Borderline borderline leprosy
Borderline Lepratomous
Borderline tuberculoid

Question 27

Multibacilliary multidrug therapy are drugs that shows

Answer 27

That show a positive skin smear test and a negative lepromin test

Question 28

Drugs for leprosy include

Answer 28

Dapsone
Clofizamine
Rifampicin

Question 29

Multibacilliary therapy checks for what type for bacteria

Answer 29

Lepratomous leprosy
Borderline Lepratomous leprosy
Borderline borderline leprosy

Question 30

Paucibacilliary therapy checks for what type for bacteria

Answer 30

Tuberculoid leprosy
Borderline tuberculoid leprosy

Question 31

Paucibacilliary multidrug therapy presents with

Answer 31

Presents with negative skin smear and positive lepromin test