Legionella Pneumophila Flashcards

to unnderstand and reproduce information on Legionella Pneumophila

1
Q

Describe the shape of L.Pneumophila

A

Slender, pleomorphic, non-fermentive coccobaccilus.

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2
Q

How is L.Pnemophila transmitted?

A

It spreads through aerosolized particles of water.
L.pneumophila binds and enters respiratory epithelial cells and inhibits autophagosome-lysosome fusion.

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3
Q

What diseases and symptoms are associated with L.Pneumophila?

A

Pontiac fever: Fever, chills, headache and muscle ache

Legionnaires disease: Fever, chills, dry cough, headache, multi-organ disease involving GIT, and CNS, Liver and kidneys.

Inflammation and microabscesses in the lung.

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4
Q

How is L.Pneumophila diagnosed in the lab?

A

For serogroup 1: a urinary antigen test is done

Sputum culture can be done as well

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5
Q

What is the treatment for L.Pneumophila infection?

A

Levofloxacin
Azithromycin

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6
Q

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A

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