Lectures 25 and 26: Inflammation Flashcards
How do vascular changes at the site of inflammation lead to the classical local signs of acute inflammation?
What are the two major components of inflammation?
What are the five mechanism underlying increased vascular permeability during acute inflammation?
What are the events that occur during white blood cell migration? Adhesion molecules and enzymes involved?
What is the mechanism of phagocytosis and degranulation?
What is opsonin? What roles does opsonin play in phagocytosis and degranulation?
What is important to know about the two classes of local mediators and plasma mediators?
What are the major roles of nitric oxide, TNF, IL1 and ROS?
What is important to know about the metabolism of arachidonic acid in inflammation and the molecular targets of the listed drugs?
What are the 4 major effects of TNF/IL-1?
What are the outcomes of acute inflammation?
What is important to know about the relationship and differences between acute and chronic inflammation?
Why are anti-PD-1 and anti-CTLA-4 antibodies useful for chronic HBC infection?
