Lectures 11 & 12 - Cysts of the Jaw Flashcards
Inflammatory Tumors
Radicular
Residual
Buccal Bifurcation
Radicular Cyst Pathology
Non-vital tooth
inflammatory process
Radicular Cyst Clinical Appearance
MOST COMMON CYST
Apex of tooth
Sometimes lateral root
Radicular Cyst Clinical Symptoms
Asymptomatic (unless exacerbated)
Radicular Cyst Radiographic Appearance
Well circumscribed radiolucency Round Not corticated Does not cross midline LOST lamina dura and PDL Root resorption
Radicular Cyst Histologic Appearance
Hyperplastic stratified squamous epithelium
Fluid filled
Inflamed CT wall
Radicular Cyst Treatment
Root canal
Extraction
Residual Cyst Pathology
Radicular or dentigerous cyst left after tooth extraction
Associated w/ becoming carcinoma
Buccal Bifurcation Cyst Pathology
Often associated with proliferative periostitis of buccal cortex
Rare
Age 5-11
Bilateral 33%
Buccal Bifurcation Clinical Appearance
Usually mandible, 1st molar
Bulge on buccal side tips tooth
Roots point lingually, cusp points buccally
Buccal Bifurcation Clinical Symptoms
Buccal tenderness
Swelling
Foul taste
Buccal Bifurcation Radiographic Appearance
Well circumscribed
Unilocular
Involves buccal furcation area and root
Occlusal film most helpful
Buccal Bifurcation Histologic Appearance
Non-keratinizing stratified squamous epithelium
Hyperplastic areas
Chronic inflammation
Buccal Bifurcation Treatment
Enucleation
Dentigerous Cyst Pathology
Associated with crown of UNERUPTED tooth Fluid build up surrounding enamel (hyperplastic follicle) Can resorb roots, enter sinus Common Age 10-30
Dentigerous Cyst Clinical Appearance
Most commonly 3rd molar
then Max. canine
Dentigerous Cyst Clincal Symptoms
No pain unless infected
Dentigerous Cyst Radiographic Appearance
Unilocular radiolucency around crown of unerupted tooth
Cyst wraps from CEJ to CEJ
Can be central (symmetrical over enamel) or lateral (asymmetrical)
Dentigerous Cyst Histological Appearance
Non-inflamed: thin non, keratinized, flat epithelium-CT interface
OR
Inflamed: hyperplastic lining, rete ridges, squamous features
Dentigerous Cyst Treatment
Enucleation
Marsupialize
Good prognosis
Eruption Cyst Pathology
Soft tissue analogue of dentigerous cyst
Develops when follicle separates from crown of erupting tooth within the gingival tissue
Eruption Cyst Clinical Appearance
Soft, translucent swelling in the mucosa overlying the crown of an erupting tooth
Usually Max. incisors and Mand. 1st molars
Eruption Cyst Radiographic Appearance
Soft tissue, duh
No radiographic evidence
Eruption Cyst Histologic Appearance
Oral epithelium w/ subadjacent inflammatory cell infiltrate
Think layer of non-keratinizing epithelium
Primordial Cyst Pathology
Cyst forms instead of tooth
Enamel organ degenerates before hard tissue develops
Often develops into a keratocystic odontogenic tumor (KCOT)
Primordial Cyst Radiographic Appearance
Round radiolucency under primary tooth
Gingival Cyst of the Newborn Treatment
Generally rupture on their own w/in 3mo of age
Gingival Cyst of the Newborn Histological Appearance
Thin, flattened lining with parakerototic (retained nuclei) surface
Lumen of cyst contains keratinaceous debris
Gingival Cyst of the Newborn Clinical Appearance
2-3mm white papules on alveolar mucosa
Usually multiples
Max more common than Mand
Gingival Cyst of Newborn Pathology
Small, superficial keratin-filled cyst arise from remnants of dental lamina
Similar to Epstein Pearls or Bohn nodules
Epstein Pearl
Inclusion cyst found in midline of palate
Bohn Nodules
Inclusion cyst found laterally on hard and/or soft palate
Gingival Cyst of Adult Pathology
Derived from rests of dental lamina
“Soft tissue counterpart to lateral periodontal cyst”
Gingival Cyst of Adult Clinical Appearance
<0.5cm papule Dome-like swelling Blue-gray Usually on facial gingiva or alveolar mucosa Most common on Mand. canine or premolars Age 40-60 Painless
Gingival Cyst of Adult Histological Appearance
Thin, flattened epithelial lining
Focal plaques may contain glycogen-rich clear cells
Gingival Cyst of Adult Treatment
Excision to confirm Dx
Will not resolve on own, deeper than newborn cyst
Excellent prognosis
Usually do not reoccur or become malignant
Lateral Periodontal Cyst Pathology
Rare Age 40-70 Botryoidal subtype Usually VITAL tooth Arise from rests of dental lamina
Lateral Periodontal Cyst Clinical Appearance
Commonly anterior to mandibular premolars
Lateral Periodontal Cyst Clinical Symptoms
Asymptomatic
Lateral Periodontal Cyst Radiographic Appearance
Well circumscribed, round, corticated
Radiolucent
Lateral to mid-root
VITAL tooth, intact PDL and lamina dura
Lateral Periodontal Cyst Histologic Appearance
Non-inflamed, thin epithelium
Flattened or cuboidal cells
Clear cells
Plaque-like thickening
Lateral Periodontal Cyst Treatment
Enucleate
Orthokeratinized Odontogenic Cyst Pathology
Orthokeratinized (NO nuclei) epithelial lining
NOT associated w/ Gorlin Synd.
Orthokeratinized Odontogenic Cyst Treatment
Enucleation w/ curettage
2% recurrance rate
Orthokeratinized Odontogenic Cyst Histologic Appearance
Orthokeratotic epithelium w/ keratohyaline granules
No prominent palisaded basal layer
Orthokeratinized Odontogenic Cyst Radiographic Appearance
Usually unilocular
Orthokeratinized Odontogenic Cyst Clinical Appearance
Typically young adult males
Most common Mand. 3rd molar
On Ddx w/ dentigenous cyst
Keratocystic Odontogentic Tumor (KCOT) Pathology
Aggressive odontogenic tumor
MOST RECURRENT odontogenic cyst (epithelial lined)
Keratocystic Odontogentic Tumor (KCOT) Clinical Appearance
Peripheral lesion in gingiva Usually interosseous, sometimes in soft tissue Post. Mandible Cheesy filling Age 10-30 M>F
Developmental Cysts
Dentigerous Eruption Primordial Gingival Cyst of the Newborn Gingival Cyst of the Adult Lateral Periodontal Orthokeratinized odontogenic Keratocystic odontogenic tumor (KCOT) Calcifying odontogenic (Gorlin) cyst Glandular odontogenic cyst
Calcifying Odontogenic (Gorlin) Cyst Pathology
Calcification within cyst
Approx. 20% of calcifying odontogenic cysts are associated with odontomas
Calcifying Odontogenic (Gorlin) Cyst Clinical Appearance
Appears as an obliteration of the vestibule
Often anterior, Max. or Mand.
Often unerupted teeth
Calcifying Odontogenic (Gorlin) Cyst Radiographic Appearance
Unilocular lucency w/ flecks of opaque calcification
33% with mixed appearance?
33% associated w/ unerupted tooth
Calcifying Odontogenic (Gorlin) Cyst Histologic Appearance
GHOST cells (eosinophilic epithelial cells w/o nuclei
Thick epithelium
Basal cells resemble ameloblasts
Cacifying Odontogenic (Gorlin) Cyst Treatment
Enucleate
Recurance is uncommon
Glandular Odontogenic Cyst Treatment
Enucleation or curettage
30% recurrence
Glandular Odontogenic Cyst Histologic Appearance
Thin epithelial lining
Mucous cells & duct-like structures in the lining
Glandular Odontogenic Cyst Radiographic Appearance
Usually multilocular
Well-defined margins
Sclerotic rim
Glandular Odontogenic Cyst Clincal Appearance
Anterior Mandible (85%)
Glandular Odontogenic Cyst Pathology
Also called Sialo-odontogenic cyst
Odontogenic cyst with glandular or salivary features
Cysts of Bone
Nasopalatine duct / Incisive canal cyst
Surgical ciliated cyst of the maxilla
Controversial:
Medial palatal cyst (more posterior nasopalatine)
Globulomaxillary (probably KCOT)
Median mandibular (doesn’t exist?)
Nasopalatine Duct / Incisive Canal Cyst Pathology
Left behind from nasopalatine duct formation
Unrelated to tooth vitality
Nasopalatine Duct / Incisive Canal Cyst Clinical Appearance
Most common NON-odontogenic cyst M=F age 30-60 Palatal swelling (rare) can push incisors anteriorly Can erode floor of sinus
Nasopalatine Duct / Incisive Canal Cyst Clinical Symptoms
Typically non-symptomatic
Salty taste = established communication w/ oral cavity
Nasopalatine Duct / Incisive Canal Cyst Radiographic Appearance
Heart-shaped
Crosses midline
Nasopalatine Duct / Incisive Canal Cyst Histologic Appearance
Stratifies squamous and/or respiratory epithelium
Wall with blood vessels and nerve trunks
Nasopalatine Duct / Incisive Canal Cyst Treatment
Small cyst: No tx
Large cyst: Ennucleate, low recurrance
Surgical Ciliated Cyst of the Maxilla Pathology
Derived from lining of the sinus entrapped during surgical closure
Surgical Ciliated Cyst of the Maxilla Clinical Appearance
Typically maxillary sinus
M>F
Surgical Ciliated Cyst of the Maxilla Radiographic Appearance
Well defined lucency
Unilocular OR multilocular
Surgical Ciliated Cyst of the Maxilla Histologic Appearance
Lined w/ RESPIRATORY epithelium
May show squamous metaplasia
Globulomaxillary Cyst
Usually KCOT
Pear-shaped radiolucency b/t lateral incisor and canine
Adjacent teeth are vital
Cysts of Soft Tissue
Lymphoepitheilial
Nasolabial / Nasoalveolar
Dermoid and Epidermoid
Thyroglossal
Pseudocysts
Not lined with epithelium
Traumatic bone cyst Stafne bone cyst Mucocele Aneurysmal bone cyst Periapical granuloma
Lymphoepithelial Cyst Clinical Appearance
Cervical, Oral, OR Parotid
Yellow color
Cervical:
Occurs along anterior border of SCM
Left (66%) > Right
Age 20-40
Oral:
Along Waldeyer ring
Lymphoepithelial Cyst Histologic Appearance
Stratified squamous epithelium with lymphoid tissue in cyst wall
Keratin in lumen (gives cyst yellow color)
Lymphoepithelial Cyst Treatment
Excision
0% recurrance
Nasolabial / Nasoalveolar Cyst Treatment
Enucleation
Dermoid and Epidermoid Cyst Treatment
Complete surgical excision
Dermoid and Epidermoid Cyst Histologic Appearance
Lined by stratified squamous epithelium
Dermoid - W/ skin appendages
Epidermoid - W/O skin appendages
Dermoid and Epidermoid Cyst Clinical Appearance
Slow-growing rubbery or doughy masses
May be yellow color
Intraoral lesions are usually midline of floor of mouth
Dermoid and Epidermoid Cyst Pathology
Derived from epithelial rests from entrapped embryonic cells
Thyroglossal Duct Cyst Pathology
Derived from remnants of thyroglossal duct after migration of thyroid gland from the base of the tongue
Thyroglossal Duct Cyst Clinical Appearance
Swelling at midline of neck below hyoid bone
F>M
50% of pts < 30 yo
Thyroglossal Duct Cyst Histological Appearance
Lined by Respiratory and/or stratified squamous epithelium
50% - thyroid tissue in wall of cyst
Thyroglossal Duct Cyst Treatment
Excision
Traumatic Bone Cyst Histologic Appearance
Empty lumen
Distinguished from KCOT b/c not filled w/ cheese
Traumatic Bone Cyst Radiographic Appearance
Scallops b/t roots of teeth
No cortication
Stafne Bone Cyst Pathology
Developmental defect containing portion of salivary gland
Stafne Bone Cyst Clinical Appearance
Focal concavity of cortical bone on lingual surface
M»F
Mucocele Pathology
Ranula - when on floor of mouth
Mucocele Treatment
May be self-limiting or require local excision
Local gland should be excised to prevent recurrence
Mucocele Histologic Appearance
Mucin surrounded by granulation tissue
Numerous foamy histiocytes
Mucocele Clinical Appearance
Dome-shaped mucosal nodule Swelling increases & decreases in size Normal to blue color Most common: -younger age -lower lip
Aneurysmal Bone Cyst Clinical Appearance
Blood-filled cavities
30% associated w/ another lesion w/i the same bone
Not a true cyst, not lined with epithelium