Lectures 1-3 (Properties of Biological Molecules) Flashcards
Covalent bonds are [stronger/weaker] than noncovalent interactions.
Stronger
Covalent bond length is [shorter/longer] than noncovalent interactions.
Shorter
Describe the connectivity of covalent bonds.
Share electrons
Describe the connevtivity of noncovalent interactions.
Attraction only
Bond between monomers of proteins.
Peptide
Bond between monormers of carbohydrates.
Glycosidic
Bond between monomers of lipids.
Ester
Bond between monomers of nucleic acids.
Phosphodiester
How is bond strength measured?
In terms of energy needed to break bonds (i.e. can be dependent on bond length)
Examples of charge-charge interaction.
Ionic bonds (i.e. NaCl), salt bridges (i.e. interaction between 2 AA in a protein)
In a vacuum, how would you measure how attractive two ions are to each other?
Coulomb’s Law
Equation for Coulomb’s Law
Where F = Force between ions in Newtons; q = Ion charges in Coulombs, k = 8.85 x 10-12 C2/J*m; r = distance between nuclei
In a biological environment, what must be accounted for when measuring how attractive two ions are to each other?
Relative permittvity
Equation for measuring that attraction of two ions in a biological environment.
Where D = Dielectric constant
Equation for measuring energy of interactions.