Lecture Test 4 Flashcards
List the types of Neurogial cells
Astrocytes Microglial Cells Ependymal Cells Olgiodendrocytes Schwann Cells
What are the 3 cell types fond in the nervous system?
Schwann Cells, Neurons, Neuroglia
Function of Astrocytes?
Most abundant, support and brace neurons and anchor to nutrient supply, form the blood-brain barrier
Function of Microglial Cells?
Defensive cell
Function of Ependymal Cells?
Permeable barrier, circulates CSF
Function of Oligodendrocytes?
Myelin Sheath
Function of Schwann Cells?
Myelin Sheath of PNS, vital to regeneration of damaged peripheral nerve fibers
Function of Neurons?
Responsive to stimuli and transmit electrical signal
Function of Neuroglia?
Support cells, surround and wrap more delicate neurons
Nissl Bodies
Clustered free ribosomes and rough ER
Neurofibrils
Bundles of intermediate filaments, maintain cell shape
Axoplasmic Transport
Movement of stuff to (Retrograde) and from (Anterograde) cell body
Cell Body
Biosynthetic center and receptive region
Axons
Conducting region of neuron
Dendrites
Main receptive and input regions (graded potentials toward cell body)
Myelin Sheath
Protects and insulates fibers
Increases transmission speed of nerve impluses
Neurolemma
Outer layer of myelin sheath
Node of Ranvier
Gaps between schwann cells
Saltatory conduction
propagation of action potentials along myelinated axons
Increases conduction velocity
Fastest neuron speed, slowest neuron speed, what makes it fast?
150 m/s = Fastest
1 m/s = Slowest
Larger diameter of axon and more myelin sheaths make it faster
How does an action potential cross a synapse?
- Action potential reaches presynaptic terminal
- Voltage gated Ca++ channels open
- Influx of Ca++
- Synaptic vesicles fuse with membrane (exocytosis)
- Neurotransmitters released across synaptic cleft and diffuse to postsynaptic terminal
- Causes Na+ channels to open and Na+ flows into postsynaptic membrane
- If threshold is reached, then action potential is initiated
- Neurotransmitter is broken down by specific enzymes in synaptic cleft
Excitatory Neurotransmitter
Causes depolarization of the membrane and promotes action potential generation
Inhibitory Neurotransmitter
Causes hyperpolarization and depresses action potential generation
One way Conduction
Refractory period ensures one way conduction.
Recovery period when Na+ channels hold to ‘recharge’