Lecture: Integument

Question 1

What are the layers of the epidermis?

Answer 1

Stratum corneum, stratum granulosum, stratum spinosum, stratum basale

Question 2

Langerhans Cells

Answer 2

Immune cells of the skin
Displays antigens on their surface
Migrates to lymph nodes
Interacts with T cells to mount immune response

Question 3

Tonofilaments

Answer 3

Cable-like rigid orientation of keratin filaments

Question 4

Lamellar granules (lamellar bodies)

Answer 4

Vesicles filled with lipids.
After apoptosis, the contents of the vesicles are released and fills the spaces between the dead keratinocytes.
Forms extracellular lipid barrier and decreases water permeability of the epidermis.

Question 5

Keratohyalin granules

Answer 5

Contain filaggrin and contributes to the formation of tonofilaments

Question 6

Filaggrin

Answer 6

Remains in the keratinocyte after death and bundles/attaches the keratin filaments together giving tonofilaments.
Mutations in filaggrin are associated with eczema

Question 7

Melanosomes

Answer 7

Melanin granules

Question 8

Anagen

Answer 8

Phase of active hair shaft and hair follicle growth

Question 9

Catagen

Answer 9

Phase of degeneration. Involution of the hair follicle

Question 10

Telogen

Answer 10

Resting phase of hair follicle