Lecture exam 3 Flashcards
Physiology of EKG
P wave: depolarization of SA node
QRS complex: ventricular depolarization
T wave: ventricular repolarization
Intrinsic conduction system
- cardiac muscle contracts independently of nerve impulses
~sets ❤️ rhythm
~ensures ❤️ muscle depolarization in ! direction (atria to ventricles)
Heart physiology
Tachycardia-rapid heart rate, over 100 bpm
Bradycardia-slow heart rate, less than 60 bpm
-Cardiac output-amt. of blood pumped by ventricle by ❤️ in 1 min
-Stroke volume- volume of blood pumped by each ventricle in 1 contraption
-❤️ rate- 75 bpm
CO= HRx SV
CO= HR (75 bpm) x SV (70 bpm)
CO= 5250 ml/min= 5.25 L/min
Details of cardiac cycle:
-1 complete heartbeat
systole=contraction
Diastole= relaxation
Atrial diastole (ventricular filling)- ❤️ is relaxed, BP is low, from atria to ventricles, semilunar valves closed
Atrial systole- ventricles relaxed, blood in ventricles, Intraventricular pressure rises, AV valves closed, ventricles closed
Ventricular systole- ventricles contract, semilunar valves open, blood goes into ventricles, atria are relaxed and filling with blood
Isovolumetric relaxation- ventricular contraption begins, pressure falls, semilunar valves close, ventricles are closed, atrial pressure increases, AV valves open
Process of hematopoiesis: where it happens? How it occurs? What controls it?
-blood cell formation
-occurs in red bone marrow
- RBC’s are eliminated by phagocytes in spleen or liver, lost cells are replaced by hemocytoblasts in red bone marrow
-erythropoietin
Steps and events of hemostasis:
1) Vascular spasms:
blood vessel constricts, slows blood flow
2) Platelet plug formation:
platelets becomes sticky and cling to collagen fibers, piles up to plug hole
3) Coagulation
Ca2+ trigger clotting, Prothrombin (inactive)–>thrombin (active), thrombin joins fibrinogen (inactive) –> fibrin (active) fibrin forms nets, forms clot
Blood and hemostasis disorders:
Thrombus- a clot in broken vessel
Embolus- a thrombus floating free in bloodstream
Thrombocytopenia- low # of platelets
Hemophilia- normal clotting factors of missing
Blood typing groups: Who can donate and recieve? Where it happens?
Blood Groups: Antibodies: Receive: Donate to:
A Anti-B A, O A, AB
B Anti-A B, O B, AB
AB neither A,B,AB,O AB
O Anti-A &B O A,B,AB,O
Blood characteristics:
sticky, opaque fluid
O2 rich blood- scarlet red
O2 poor blood-dull red
ph 7.35-7.45
Formed elements: (least to greatest)
Neutrophils - # ^ during infection, functions as phagocytes at infection, eats bacteria
Lymphocytes -Large w/ nucleus, inside lymphatic tissue, produce anit-bodies
Monocytes- largest WBC, function as phagocytes , eat cancer cells and chronic cells
Eosinophils - kills worms
Basophils - release histamine & heparin to innflammation