Lecture 90 - Antiretrovirals Flashcards
1
Q
AZT (Zidovudine) is an _____ active nucleoside _____ transcriptase inhibitor. High concentrations can be achieved in the _____, and it crosses the ____.
A
Orally active
Reverse transcriptase
CNS
Placenta
2
Q
Lamivudine is also known as _____. It decreases the emergence of resistance!
A
3TC
3
Q
Tenofovir is also known as ____.
A
TDF
4
Q
______ is a protease inhibitor that is given in combination with other protease inhibitors (i.e. lopinavir) to prolong their half-life (decreased metabolism by cytP450).
A
Ritonavir
5
Q
_______ is administered IV and binds CD4+ T-cells, inhibiting viral entry into host cell, but it does not inhibit CD4-dependent immunity. It is used for MDR HIV
A
Ibalizumab
