Lecture 9: tHe Ageing Brain

Question 1

What are the 3 regional alterations in ageing brain?

Answer 1

Nervous system tissue
Cellular
Molecular

Question 2

How many neurons are in the brain normally?

Answer 2

100 billion

Question 3

What fluid increases in the brain with age?

Answer 3

Cerebrospinal

Question 4

The loss of brain volume is primarily due to what?

Answer 4

Grey matter

Question 5

Which gray matter declines the most?

Answer 5

Prefrontal gram matter

Question 6

What regions tend to be preserved in the human brain?

Answer 6

Sensory and motor regions

Question 7

What is a key subregion of the prefrontal cortex affected by ageing?

Answer 7

The orbitofrontal cortex

Question 8

What is the orbitofrontal cortex required for?

Answer 8

Updating and storing information about outcomes that will follow choices

Question 9

What are the two hypothesis of the cause of grey matter loss?

Answer 9

Neuronal cell loss

Loss of dendrites and synapses

Question 10

What measures synaptic strength”

Answer 10

Long term potentiation