Lecture 9 Temp Flashcards

0
Q

The continuous venous plexus in the subcutaneous tissue is supplied by what?

A

inflow of blood from capillaries from dermis

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1
Q

what kind of tissue especially acts as heat insulators?

A

Skin and subcutaneous tissue

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2
Q

how great can the rate of inflow be?

A

30% of CO

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3
Q

how big of an increases in conductance is there between vasoconstricted to vasodilated?

A

8x

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4
Q

vasoconstriction is controlled by what?

A

sympathetic system in response to core and environmental temps

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5
Q

what are the 3 mechanisms of heat loss from the skin?

A

radiation, convection, conduction

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6
Q

what is convection

A

heat loss from body bc of air currents

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7
Q

what is conduction?

A

KE of the skin transferred to air IF air is colder than body

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8
Q

what is radiation?

A

loss in the form of infared heat rays (most common, 60%)

radiated by all objects NOT at ABSOLUTE ZERO

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9
Q

True or False:

Water has a specific heat several thousand times less than air.

A

False, greater than air, same with heat loss

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10
Q

what rate does insensible perspiration occur at per day and how many Cals per day?

A

600-700 ml/day

16-19 Cal/day

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11
Q

what part of the brain does the stimulation for sweating occur?

A

anterior hypothalamus pre-optic area

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12
Q

what type of nerve fibers and what hormones stimulate it?

A

cholinergic

Epi and NE

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13
Q

what is the precursor secretion similar in composition to?

A

plasma w/o proteins

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14
Q

What ions are present in precursor secretion and in what concentration?

A

Na+: 142
Cl-: 104

Duh, sweat is salt

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15
Q

In strong stimulation of sweat glands what is reabsorbed?

A

little water

ducts reabsorb only half NaCl

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16
Q

True or False
An acclimated person normally produces 1 liter sweat per hour while a person unacclimated to hot weather produces 2-3 liters sweat per hour?

A

False, reverse

if you are acclimated, you will sweat more because your body knows how to get rid of heat

17
Q

what is the heat removal factor? what is acclimation due changes in?

A

10x

internal sweat glands

18
Q

what are the 2 areas of the brain that affect body temp?

A

anterior hypothalamic pre-optic

pre-optic

19
Q

which area of the brain contains both cold and heat-sensitive neurons?

A

anterior hypothalamic pre-optic

20
Q

what happens when the pre-optic area is heated?

A

immediate dilation of blood vessels, profuse sweating, inhibition of excess heat production

21
Q

how do you reduce body heat?

A

vasodilation, sweating, inhibition of thermogenesis

22
Q

how do you increase body heat?

A

vasoconstriction, piloerection, increase thermogenesis

23
Q

what is thermogenesis?

A

shivering, metabolic pathways, thyroxine secretion

24
Q

where is the primary motor area for shivering located?

A

dorsomedial portion of posterior hypothalamus

25
Q

what activates shivering?

A

cold signals from skin and spinal cord

26
Q

how does the dorsomedial portion of the post. hypothalamus initiate shivering?

A

transmits signals into lateral column of spinal cord
signals increase muscle tone, shivering starts when it goes above a certain level
may involve muscle spindle stretch reflex

27
Q

what is chemical thermogenesis?

A

increase cellular metabolism due to sympathetic stim (NE in blood)

28
Q

what does Epi/NE do?

A

uncouples ox phos

29
Q

what is the relationship between thermogenesis and brown fat?

A

direct

30
Q

what effect does inc. thyroxine output have on cell metabolism?

A

increases the rate of cellular metabolism throughout the body (chemical thermogenesis

31
Q

what is the critical body core temp?

A

37.1 C, 98.8 F

32
Q

The level at which sweating begins or shivering begins in order to return to critical core body temp is called what?

A

set-point

33
Q

what is the feedback gain of the temp control system?

“ “ baroreceptors in arterial pressure?

A

27 –> (28/1) - 1

less than 2

34
Q

skin temp changes are primarily responsible for what?

A

physiological mechs that alter the critical set point

35
Q

what are pyrogens and give some examples

A

pyrogens induce an abnormal rise in body temperature, set-point to rise

ex. pathogens and bacteria

36
Q

how does IL-1, prostaglandins effect fever?

A

induce fever (Inc. temp)

37
Q

How does aspirin and arachidonic acid effect fever?

A

Reduce fever

38
Q

what are some febrile conditions

A

chills - set point higher than normal

crisis/flush - set point lower than normal

39
Q

when is heat stroke likely to occur?

A

at 105-108 degrees F

40
Q

what are the symptoms of heat stroke? how is related to circulatory shock?

A

dizziness, vommiting, loss of consciousness

loss of electrolytes and fluid

41
Q

what temp point does the hypothalamus lose its ability to regulate temp?

A

85 degrees F