Lecture 9 (Respiratory channelopathies 2) Flashcards
1
Q
How much CFTR function is needed for treatment to be successful?
A
15%
2
Q
How do we block contamination from sodium channels when testing CF treatments?
A
Amiloride blocks the sodium channel ENaC so its not a contamination in the recording
3
Q
What does more mature CFTR mean?
A
More CFTR is going into the membrane
4
Q
What is combination therapy?
A
Combining more than one form of treatment, could be greatly beneficial