Lecture 9 (Respiratory channelopathies 2) Flashcards

1
Q

How much CFTR function is needed for treatment to be successful?

A

15%

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2
Q

How do we block contamination from sodium channels when testing CF treatments?

A

Amiloride blocks the sodium channel ENaC so its not a contamination in the recording

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3
Q

What does more mature CFTR mean?

A

More CFTR is going into the membrane

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4
Q

What is combination therapy?

A

Combining more than one form of treatment, could be greatly beneficial

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